Dr. Nguyen
leads multiple clinical trials at U-M to develop new therapies in MPNs.
Not exact matches
The company's
leading program, a differentiated PPAR gamma agonist (MIN - 102) that has
multiple CNS indications, has successfully completed a phase 1
clinical trial and is ready to move into a phase 2/3 study with adult AMN patients.
The company's
lead program, now in phase I
clinical trials, is a differentiated PPAR gamma agonist (MIN - 102) that has potential in
multiple CNS indications.
His work in designing anticancer compounds had
led to millions of dollars in funding and
multiple patents, as well as two compounds in
clinical trials.
The new
clinical trial,
led by Braley and funded by the National
Multiple Sclerosis Society, will investigate whether cognitive function in MS patients improves when sleep apnea is treated.
This
clinical trial is the culmination of long - standing research
led by Professor John Greenwood at the UCL Institute of Ophthalmology showing the potential therapeutic benefits of using statins to treat autoimmune diseases such as
multiple sclerosis and uveitis.
The study is investigator
led and has therefore focused on
clinical need, targeting patients with progressive
multiple sclerosis in whom most disability is incurred... The study also reports a predominant effect on neurodegenerative rather than inflammatory outcomes, suggesting a novel mechanism of action that might be suitable as combination treatment with immunomodulatory treatments... Further phase 3 studies to measure the effect of simvastatin on sustained disability, particularly in patients with non-relapsing secondary progressive and primary progressive
multiple sclerosis, are clearly needed, but this
trial represents a promising point from which to develop
trials of progressive disease.»
She is an active
clinical trialist,
leading numerous
multiple clinical trials of molecularly targeted agents for advanced cancer patients.