Sentences with phrase «leads to cancer progression»

Using human colon cancer cells and primary human fibroblasts isolated from tumors and adjacent normal tissues, Alexandros Glentis and colleagues at the Institut Curie addressed the question of whether the cancer cells or the CAF cells were responsible for the breakdown of the basement membrane that leads to cancer progression.

However, other studies in mice with breast cancer show that once cancer has already been initiated, stress can lead to increased rates of tumor spread and metastases.26 Similarly, when mice were injected with leukemic cells and stressed physically and physiologically with injections of adrenaline, cancer progression occurred.27 Some scientists even propose that, while necessary in many cases of cancer, undergoing surgery may cause enough stress to lead to tumor promotion and progression.28 Therefore, it seems like acute stress may help fight cancer, chronic stress may help cause it, but once cancer is present, both acute and chronic stress may lead to cancer progression.

acute stress may help fight cancer, chronic stress may help cause it, but once cancer is present, both acute and chronic stress may lead to cancer progression

Not exact matches

Meanwhile, cancer genome projects have yielded unprecedented insights into the cellular signaling pathways that drive the development and progression of cancer — information that has led to effective therapies tailored for individual patients.

A drug used to treat men with late - stage prostate cancer proved effective in stemming progression of the disease in research participants who had not yet received chemotherapy and extended their survival, according to results from a multi-national Phase III clinical trial led by the Knight Cancer Institute at Oregon Health & Science University (cancer proved effective in stemming progression of the disease in research participants who had not yet received chemotherapy and extended their survival, according to results from a multi-national Phase III clinical trial led by the Knight Cancer Institute at Oregon Health & Science University (Cancer Institute at Oregon Health & Science University (OHSU).

The research team, led by Professor Yoshiaki Ito, Senior Principal Investigator at CSI Singapore, found that a modification called phosphorylation made to RUNX3 promotes cancer progression by allowing cell division.

Investigating how organs far from tumors contribute to cancer progression should lead us to ways of manipulating those systemic activities in therapy.

There is really no reliable method for recapitulating the metastatic progression from a primary tumor in the colon to the liver,» says Omer Yilmaz, an MIT assistant professor of biology, a member of MIT's Koch Institute for Integrative Cancer Research, and the lead senior author of the study, which appears in the May 1 issue of Nature Biotechnology.

«Understanding the differences among lung cancers also could lead to innovations in treatment strategies and allow us to overcome drug - resistance, relapse and disease progression.»

LA JOLLA — Scientists at the Salk Institute for Biological Studies have identified a key genetic switch linked to the development, progression and outcome of cancer, a finding that may lead to new targets for cancer therapies.

He concluded that the improvement in progression - free survival and potential for overall survival benefit should lead to a phase III trial of this therapy option in small - cell lung cancer.

11/13/2008 How Eating Red Meat Can Spur Cancer Progression Researchers at the University of California, San Diego School of Medicine, led by Ajit Varki, M.D., have shown a new mechanism for how human consumption of red meat and milk products could contribute to the increased risk of cancerous tumors.

I have an ongoing research interest in integrated characterization of cancer genomes, defining the DNA - level somatic and germline interactions that lead to cancer onset and progression.

Preliminary evidence from the small clinical trial, led by William Gillanders, MD, also suggests that the vaccine primed the patients» immune systems to attack tumor cells and helped slow the cancer's progression.

Remember, inflammation makes the immune system less effective in doing its job, and a less effective immune system leads to progression of cancer cells!

«Our underlying hypothesis is around inflammation and, in particular, we believe that inflammation from a variety of sources is leading to prostate cancer progression,» she says.