The determination of relevance to self of verbal statements of differing emotional valence involved
left ventrolateral prefrontal cortex (left inferior frontal gyrus, BA 47), right caudate and right cingulate gyrus (BA 24).
Personal Distress was associated with amygdala and hypothalamus activation, Empathic Concern with the
left ventral striatum,
ventrolateral prefrontal cortex (VLPFC), and supplemental motor area (SMA) activation, and Fantasy with the septal area, right SMA and VLPFC activation.