Sentences with phrase «length huntingtin»

This interaction wasn't seen with normal - length huntingtin RNA.

Because of the interaction with the helper complex, the cells made more extra-length than normal - length huntingtin protein.

Because the helper complex makes translation more efficient, the result of this interaction was that the cells made more extra-length than normal - length huntingtin protein.

Not exact matches

When they stained brain samples taken from human Huntington's victims, they found that the characteristic globs consist of full - length mutant huntingtin, rather than peptide fragments from the mutant.

Correlation of CAG repeat length between the maternal and paternal allele of the Huntingtin gene: evidence for assortative mating.

With these details of translation in mind, a team of Huntington's disease researchers, led by Susann Schweiger of The Max Planck Institute for Molecular Genetics in Berlin, decided to study how huntingtin proteins are made from genes of different lengths.

Here, we examine wild - type huntingtin's localization in cultured cells by expressing the full - length human protein tagged with enhanced green fluorescent protein (EGFP) within its unspliced genomic context.

Until now, it was thought that all the huntingtin RNA in the cell was the full - length version.

In addition, HDAC4 reduction delayed huntingtin (Htt) aggregation in CNS tissue from both the R6 / 2 and HdhQ150 full length KI mouse model of HD [1].