Sentences with phrase «leptin crosses the blood brain barrier»
Less leptin crosses the blood brain barrier, less binds to its receptors and the brain sends the signal to let you know it's time to eat again.
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It also reduces the amount of leptin crossing your blood - brain barrier by raising triglycerides.
Fructose raises your insulin and your triglycerides, which effectively reduces the amount of leptin crossing your blood - brain barrier.
It is crucial for leptin to cross the blood brain barrier, because when it doesn't, the brain sends the message that you are hungry and needs to eat.
Researches from St. Louis and Japan (Banks A, Coon AB, Robinson SM, Moinuddin A, Shultz JM, Nakaoke R, Morley JE, et all, Triglycerides induce leptin resistance at the blood - brain barrier) found that leptin's ability to cross the blood brain barrier is interrupted by triglycerides (fats found in the blood stream).
It also raises your insulin and your triglycerides, which effectively reduces the amount of leptin crossing your blood - brain barrier.
However, we have a problem when there are lots of leptin stores, but they have trouble crossing the blood brain barrier.
If leptin signalling is weak — ie, if our body fat levels are too low, or if we exercise too often — then the lack of leptin crossing the blood - brain barrier into the hypothalamus signals to the hypothalamus that the body is starving, and certain extraneous bodily functions such as reproduction cease.
Thus, it is possible that the CNS abnormalities observed in ME / CFS patients can be explained, at least in part, by the ability of leptin and resistin to cross and / or disrupt the blood — brain barrier (46).