A traditional technique in avoiding vaccination reactions is to avoid leptospirosis vaccine, giving the rest of the Distemper combination vaccine without it.
Talk with your vet about optional vaccinations for bordetella, coronavirus, leptospirosis, and Lyme disease, because if these are needed or wanted, the first bordetella vaccine should be given at six to eight weeks of age.
A traditional technique in avoiding vaccination reactions is to avoid leptospirosis vaccine, giving the rest of the distemper combination vaccine without it.