Sentences with phrase «less amyloid»

In that subset, people who had high education levels and who had continued to learn throughout their lives had less amyloid plaque, compared to those with high education levels who did not continue to challenge their mind.

On average they had around 67 % less amyloid plaques than those receiving no treatment and those that were present were much smaller in size.

With a combination approach, animals finished the study with less amyloid than they had at the start of treatment.

When the research team deleted a gene that allows heparan sulfate to adhere to the surface of neurons, they found much less amyloid plaque.

In tests on human brain cells engineered to make more normal prions than usual, Hooper found that the cells secreted far less amyloid beta peptide than they would ordinarily.

RIDE THE WAVES Compared with a mouse that received random brain stimulation (right), a mouse stimulated to produce more gamma waves (left) had less amyloid - beta (green) in its hippocampus.

Not exact matches

In a culture dish microglia that were modified to make a lot of TREM2 gobbled more amyloid and removed more dying neurons, compared with microglia having less of the protein.

Curiously, though, one strain racked up tons of brain amyloid whereas another ended up with less than usual.

About 20 proteins share the ability to clump together to form distinctive «amyloid fibrils» that contribute to Alzheimer's, Creutzfeldt - Jakob disease, and a variety of lesser - known disorders.

«Less oxidation could prevent misfolding to a certain degree, perhaps even to the point that it slows the aggregation of beta - amyloid peptides, which is believed to be the ultimate cause of Alzheimer's.»

While acute sleep deprivation is known to elevate brain beta - amyloid levels in mice, less is known about the impact of sleep deprivation on beta - amyloid accumulation in the human brain.

Instead of stirring up powerful T cells through an injected amyloid vaccine, they used a nasal spray containing two drugs that provoke a less robust but more manageable immune response.

If the precursor proteins can be cut in such a way as to make the resultant amyloids shorter and less sticky, then they resist clumping and won't form plaques.

While the buildup of sticky proteins called amyloid plaques in the brain has been repeatedly linked to Alzheimer's disease, the role of blood in the formation of the condition has been less clear.

The operationalization of mild cognitive impairment (MCI) led to targeting earlier symptomatic cases of the illness and treatment strategies based less on pathology and more on a chance to halt or slow decline than there would be earlier in the disease.1 With the development of amyloid imaging, MCI due to AD diagnosis was refined, 2 and early - stage AD was extended further to include preclinical AD, 3 wherein a positive amyloid positron emission tomography (PET) scan or diagnostic low levels of cerebrospinal fluid β - amyloid (Aβ) indicated the presence of pathology in people who were cognitively normal.

Their research revealed that the brains of the coffee drinkers actually showed less development of amyloid plaques, a hallmark of Alzheimer's disease.

Reduced metabolic activity of brain cells and neurons means less brain activity and a decreased ability of the brain to clear abnormal structures like the beta - amyloid plaques associated with Alzheimer's disease.

Sleep promotes memory consolidation and that is why this process is abnormal in the elderly (who sleep less) and in those with diseases such as Alzheimer, in which amyloid accumulates.

«People who received a high - saturated - fat, high - sugar diet showed a change in their ApoE, such that the ApoE would be less able to help clear the amyloid,» said research team member Suzanne Craft, a professor of medicine at Wake Forest School of Medicine.