Sentences with phrase «less effective drug»

Clinical trials are stopped early when results are so clear that it would be unethical to continue treating patients on the control arm with the less effective drug.

Instead migraine sufferers may be given other, less effective drugs such as opioid narcotics.

Finally, the supplements partisans accuse the pharmaceutical industry and mainstream medicine of being greedy, out for the big bucks, and eager to cover up miracle drugs that would end disease and, in consequence, eliminate the need for their own less effective drugs.

Not exact matches

Drugs that were effective at warding off infections decades ago are now less potent because the bacteria they were designed to kill have developed defence mechanisms.

And Valeant's round - about method of funding research, if that's what it's actually doing, seems a lot less cost effective, with all of the bankers and lawyers and hedge fund managers taking chunks of deals than if drug companies directly devoted a portion of their sales toward finding new drugs.

And don't worry, the lower cost doesn't mean the drug is less effective — brand and generic drugs have the same standards of quality and clinical effectiveness.

«If there was serious testing and the fighters believed that the testing was effective, they'd be less inclined to use prohibited drugs.

less than or equal to lamivudine Acquired Immune Deficiency Syndrome Antiretroviral therapy, usually means 1 - 2 drugs, used in early studies Antiretroviral zidovudine (also known as ZDV) Breastfeeding Baby Friendly Hospital Initiative Breastfeeding and HIV International Transmission Study Combined antiretroviral therapy Centers for Disease Control and Prevention Deoxyribonucleic Acid Exclusive Breastfeeding Enzyme Linked Immunosorbent Assay Food and Agrigulture Organization Fixed dose combination ART, e.g., lamividine, stavudine, and nevirapine Highly Active Antiretroviral Therapy, 3 or more drugs for more effective treatment used in later studies Human Immunodeficiency virus International Atomic Energy Agency Infant feeding Infant and young child feeding Lopinavir cubic millimetre Mother - to - Child Transmission of HIV Non-governmental organization Nevirapine Polymerase Chain Reaction People Living with HIV Prevention of Mother - to - Child Transmission Replacement Feeding Ritonavir Ribonucleic acid, one of the three major macromolecules (along with DNA and proteins) that are essential for all known forms of life single dose NVP United Nations Agencies Joint United Nations Programme on HIV / AIDS United Nations Population Fund United Nations Commissioner for Refugees United Nations Children's Fund U.S. Agency for International Development World Alliance for Breastfeeding Action United Nations World Food Programme World Health Assembly WHO 2010 Guidelines on HIV and infant feeding World Health Organization Zidovudine (same drug as AZT)

Drug companies used to stay one step ahead by continually introducing new medications, but bacteria have been mutating rapidly in response, making the drugs less effective.

The Labour MP was the sole challenger to Vaz for the post in June 2015, when she stated: «My aim is fewer victims of crime, effective and fair immigration control, less drug abuse and an end to home grown terrorism.»

Studies of the drug abroad have shown that it is effective and has fewer side effects compared to other corticosteroids, namely less associated weight gain.

Newer drugs may cause less abuse and addiction than morphine and they may act longer or be more effective by mouth, but no drug has been discovered that is more effective than morphine for the relief of severe pain of all kinds.

It was the most effective drug available for tonic - clonic (grand mal) seizures until 1938, when Dilantin, a far less sedating drug, displaced it.

Less than half the surgeries, drugs, and tests that doctors recommend have been proved effective.

(Five of the three - drug combinations were less effective than they expected, and the other 13 groupings performed as they predicted.)

African Americans are less supportive than either whites or Hispanics of allowing access to experimental drug treatments before such treatments have been shown to be safe and effective.

«This target can be used to develop a drug that would hopefully, combined with chemotherapy, be more effective and less toxic.»

In contrast to viral proteins, the host targets are less prone to mutations and thus drugs targeting them could be more effective against viruses, which mutate easily.

Achim Harder, head of anthelmintic research at Bayer, the German company that makes praziquantel, says it is not clear why the drug is less effective in Senegal.

While morphine continues to be one of the primary drugs used for the treatment of severe or chronic pain, it is often less effective in females.

The authors point to studies of harmful and beneficial effects of thrombolytic and antiarrhythmic drugs for myocardial infarction, for example: «Not only would systematic reviews... have reduced waste resulting from unjustified research, they would also have shown how to reduce morbidity and sometimes mortality, both in patients allocated to relatively less effective or actually harmful treatments in unnecessary trials, and in patients generally,» the authors write.

Antibiotics are unique among drugs as the more they are used, the less effective they become and over time resistance develops.

One was that all studies were short - term, less than six months, and all studies on effective drugs had more than 9 percent of participants drop out due to adverse effects.

When that happens, patients have to switch to a new drug combination that can be less effective than the previous treatment.

A new study led by UC Berkeley researchers found that a policy called reference pricing is effective at encouraging patients to spend significantly less on prescription drugs by choosing cheaper drugs over name brand options.

(5) This could be because the drugs are most effective 3 - 6 hours after symptoms begin and women are less likely than men to reach the hospital within this time period.

Current antimalarial drugs are becoming less effective as the parasite develops resistance to the drugs, making the search for new targets that can kill all species of malaria critical.

Instead of a six - month regimen, these drug - resistant strains can take 18 months to several years to treat, with antibiotics that are more toxic and less effective.

Discouraged by recent findings that antiviral drugs such as zidovudine (AZT), ddI and ddC are less effective than had been hoped, many people with HIV, and their doctors, are now confused about how and when to use them.

«We need new drugs and shorter regimens which are more effective, less toxic and widely available in the European region.

The revelation that Notch1 serves different functions, and knowing which parts of the protein govern each function, allows for the development of new drugs that are both more effective and less toxic.

This molecule plays an important role in some cancers and drugs that block it are already available to patients — but making drugs that are more effective and less damaging to healthy cells could lead to patients living longer and reduce side effects.»

As a result, Shaw's team has begun another clinical trial with a more potent ALK inhibitor — LDK378, a drug made by Novartis — that might take over when Xalkori becomes less effective.

«Our research adds weight to the idea that effective antifungal drugs can target even those mitochondrial proteins that are highly conserved in humans and fungi, and that this could be a way to make a broad spectrum antifungal combination therapy that would be less susceptible to resistance,» says Benjamin Vincent, a former graduate student in Whitehead Member Susan Lindquist's lab who is now a scientist at Yumanity Therapeutics.

So far the yield is less than cost effective, but Keasling says he will soon have his bacteria producing industrial quantities of the drug at a price affordable in the developing world, where malaria runs rampant.

Reasons for the attrition rate included absence of effective drugs, timing of genomic testing in the course of a patient's disease, less - than - optimal access to targeted drugs or clinical trials, and patient and provider preferences.

For most painful conditions, acetaminophen and non-steroidal anti-inflammatory drugs have been shown to be equally or more effective with less risk of harm than opioids.»

The early intervention strategy is most frequently used for drug testing in AD because drug candidates assayed in AD transgenic mice at the stage when pathology is already present are generally less effective [27 — 30].

Such approaches are becoming less effective due to the emergence of pesticide - resistant mosquito populations and drug - resistant strains of the parasite.

Most are still being cured, but as artemisinin becomes less effective, its partner drug will have to mop up more surviving parasites.

Clinical application of pharmacogenomics knowledge will result in less «trial and error» prescribing and more efficacious, safer and cost - effective drug therapy.

Older drugs, which will usually be generic versions, are often as effective as newer ones for certain conditions but are usually a lot less expensive.

«We should look also at older drugs that may have been discarded, and perhaps work more to understand the mechanism of action of acetaminophen to develop a new, more effective and less toxic drug of the same class, or develop new classes of painkillers,» Moore suggested.

St. John's wort may also make other medicines less effective, such as birth control pills, some HIV drugs, and blood thinners like Warfarin.

«The data, particularly for low back pain, seems to show the longer you're on it the less effective it is, and the more of the drug you need to get an effect,» Michna said.

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According to the Jan 5 JAMA study, if your Hamilton score is less than 24, then placebo is just as effective as antidepressant drugs.

According to the Jan 5 JAMA study, if the Hamilton score is less than 24, then placebo is just as effective as SSRI antidepressant drugs.

Nutritional ketosis has received a lot of attention by cancer researchers in recent years, and many studies show it has great potential not just as a form of cancer prevention but also treatment — in combination with other treatments such as chemotherapy and radiation.16 Research is looking at whether non-toxic metabolic therapies and drug cocktails may be just as effective, with less toxicity.

However, I learned quickly that when you keep on taking these drugs you also build up tolerance in the body, which means that the drug with extended usage, will become less and less effective.