Ferumoxytol leaks
out of blood vessels in areas of inflammation and is taken up by immune cells called macrophages, which congregate at sites of inflammation.
Compared with unheated mice, the animals with the faux fever had twice as many white blood cells migrating
out of the blood vessels and into the lymph tissue that lines the skin and gut, which is where they need to be to attack incoming pathogens.
The results suggested that the dye leaked
out of the blood vessels, flowed through the dura and into neighboring lymphatic vessels.
Hospitals not only provide optimum conditions for the evolution of superbugs, but they also provide a plethora of inviting pathways for bacteria to get inside human bodies: open wounds from surgical incisions, catheter tubes running in and
out of blood vessels and urinary tracts, and ventilators inserted through noses or throats and into windpipes.
By masking JAM - C, H225 was able to prevent the cells from migrating
out of the blood vessels.
It keeps fluid from leaking
out of blood vessels.
Dr. Ley and team focused on how neutrophils attach to the blood vessel wall, rather than their migration
out of the blood vessel.
HDL - high density lipoprotein, which is cardio - protective for men and women because it helps transfer cholesterol
out of blood vessel walls back to the liver for other uses.
-- Deficiency of albumin (protein that is made by the liver) in your blood as water leaks
out of blood vessels more easily when there isn't enough of this protein.
This overloads the atrium and causes fluid to leak
out of the blood vessels into the lungs (known as pulmonary oedema).
The clinical signs occur when the pressure in the enlarged heart chambers cause fluid to leak
out of the blood vessels into the lungs (called pulmonary edema or «water on the lungs») and sometimes the belly (ascites).
This leads to a «back - up» of blood in the lungs, which can result in fluid leaking
out of blood vessels and accumulating in lung tissue, resulting in cough.
Not exact matches
It was carried
out in June 2008, and was a complete success, with no hint
of any rejection, and with the local
blood vessels growing normally in the transplanted organ.
It is a collection
of blood leaking completely
out of an artery or vein, but confined next to the
vessel by the surrounding tissue.
Biofilms form endocasts and once dissolved
out of the bone, mimic real
blood vessels and osteocytes.
Is it because they are here to suck every
blood vessel dry
out of this club?
Ferguson was at times combustible and volatile, walking
out of press conferences, arguing with the media whilst his face threatened to pop a number
of major
blood vessels but he would never have dragged the club into battle.
Another serious health concern to watch
out for is Kawasaki disease, which is a rare condition that occurs in children and involves inflammation
of the
blood vessels.
Once the placenta is
out of your body your uterus will continue to contract, this time to help seal off the
blood vessels where the placenta implanted itself into the endometrium.
But is it fair to equate historical constraints with defects in describing how vertebrate photoreceptors are on the back
of the «inside -
out» retina, shadowed by
blood vessels and overlying cells?
To find
out, the researchers injected a cloned telomerase gene into cultured cells from retina, skin, and
blood vessels, all
of which are associated with degenerative, aging - related diseases.
Take the practice
of cleaning
out the carotid arteries, the large
blood vessels that run up each side
of the neck.
The network
of blood vessels in the brain regulates the transport
of energy and materials in and
out of the brain — forming what is known as the
blood - brain barrier (BBB).
It turns
out that one recruits the other in the
blood vessels of mice.
In the image on the left, many green - labeled neutrophils carrying the C5a receptor have moved
out from the grey
blood vessel into the joint
of a mouse in which inflammatory arthritis has been induced.
Nowhere is this more true than in the brain, where
blood vessel walls are tightly knit, keeping most large molecules from seeping
out of the bloodstream and into brain tissue.
Until now, many scientists believed that
blood flow within the brain was solely controlled by changes in the diameter
of arterioles,
blood vessels that branch
out from arteries into smaller capillaries.
After analyzing the videos, they found that, as the animal dipped its tongue in and
out of the flower, tiny
blood vessels on the hairs
of its tongue became engorged with
blood, prompting the hairs to stand straight up and drag even more nectar up from the flower.
Scientists at the Wyss Institute at Harvard University set
out to solve the mystery
of how
blood flow keeps the
vessels intact and, to their surprise, discovered a completely new cell signaling pathway that is a promising target for drugs to treat a variety
of debilitating conditions.
In AMD, the retinal pigment epithelial (RPE) cells that support the cells in the eye that detect light wear
out, and there is also the growth
of abnormal, leaky
blood vessels below the retina.
GM - CSF is thought to act by moving progenitor cells
out of the bone marrow so that they can replenish the linings
of blood vessels.
Dr Claus Jorgensen, who led the research at The Institute
of Cancer Research, London, and at Cancer Research UK's Manchester Institute at the University
of Manchester, said: «The next step is to figure
out how to keep this receptor switched on, so that the tumour cells can't leave the
blood vessels — stopping breast cancer spreading and making the disease easier to treat successfully.»
Now, scientists have discovered just how they do it without permanently damaging
blood vessels, which they slip into and
out of up to 10 times each day.
Knowing that insulin can stimulate the growth
of blood vessels, «our expectation was that knocking
out insulin signaling in these cells might slow the growth
of blood vessels and reduce tumor formation in these mice,» Rask - Madsen says.
Nature gets around this problem by permeating tissue with a network
of tiny, thin - walled
blood vessels that nourish the tissue and remove waste, so Kolesky and Lewis set
out to mimic this key function.
Biofilms form endocasts and once dissolved
out of the bone, mimic real
blood vessels and osteocytes.
This suggests that tumors send
out signals that encourage lymph duct growth â $ «a parallel to the well - known ability
of tumors to drive growth
of blood vessels nearby.
Each time a human heart beats,
blood rushes
out of the muscular pump and winds through 60,000 miles
of blood vessels.
To find
out whether an oral form
of minoxidil can remodel the
vessel's wall to reduce
blood vessel stiffness and enhance
blood flow to the brain, researchers studied the drug's effects in mice.
A research team working with mice has discovered that
blood vessels and muscles in the heart can regulate the uptake
of fatty acids from our diet, and has worked
out how they do this.
Even then, Ingber notes, «you need to know how the drug crosses in and
out of the bloodstream across the
blood vessel wall, and from one tissue and into another tissue» — something organoids can't yet test.
By the end
of the two years, we will have worked
out how good this experimental approach is at preventing
blood vessel growth, and also any possible side effects on healthy eye cells.
Delivering drugs to the brain is complicated because the three - pound organ is shielded by a complex network
of blood vessels, called the
blood - brain barrier, that keeps
out foreign substances.
TNF not only initiates a cascade
of other chemical messengers but also increases
blood -
vessel permeability, allowing white
blood cells to pass easily
out of the capillaries to reach the site
of an infection.
It is already known that a network
of blood vessels in the brain regulates the transport
of energy and materials into and
out of the brain - this is known as the
blood - brain barrier (BBB).
That was the research niche that we set
out to explore to see if we could find a new way
of targeting the abnormal
blood vessel growth that occurs in wet AMD.
Choroidal neovascularization is the
out -
of - control growth
of fragile, leaky
blood vessels that distort vision and damage the retina, which is seen in both diabetic retinopathy and the «wet» form
of age - related macular degeneration (AMD).
In the meanwhile, your arteries keep pulling
blood into the contracted muscle which makes a lot
of intra-muscular
blood plasma which seeps
out of your capillaries into the space between your muscles and
blood vessels, known as the interstitial area.
When you drink cold liquids, such as iced tea or ice water, the same thing happens to your digestive tract:
blood vessels constrict and
blood moves
out of the area.
In a healthy person without chronic,
out -
of - control inflammation, such damage to the
blood vessels would be quickly fixed.