They compared the effectiveness of the combination treatments with just treating
the leukemia by chemotherapy or inhibitors alone.
Not exact matches
Inspired
by his own bout of
leukemia to try to find a better cancer treatment, retired broadcasting station owner Kanzius guessed that as an alternative to
chemotherapy, he could inject tumors with metal ions, then use radio waves to heat the metal and destroy cancerous cells.
By creating an experimental model of
leukemia in mice whose cancer cells were resistant to
chemotherapy the team was able to caracterize these cells» metabolic profile and observed certain modifications at the level of the mitochondria.
New research posted online
by the Nature journal
Leukemia suggests blocking part of a DNA repair complex that helps some types of leukemia resist treatment can increase the effectiveness of chemotherapy and enhance s
Leukemia suggests blocking part of a DNA repair complex that helps some types of
leukemia resist treatment can increase the effectiveness of chemotherapy and enhance s
leukemia resist treatment can increase the effectiveness of
chemotherapy and enhance survival.
There is no known way to prevent most types of
leukemia, though some types may be prevented
by avoiding high doses of ionizing radiation, exposure to the chemical benzene, smoking and certain types of
chemotherapy.
As part of the new study, the researchers showed that intact axons without Phr1 were protected from the damage caused
by vincristine, a
chemotherapy drug used to treat
leukemia, neuroblastoma, Hodgkin's disease and non-Hodgkin's lymphoma, among other cancers.
One reason for this, explains Hai - Hui (Howard) Xue, MD, PhD, UI professor of microbiology and immunology, is that there are two kinds of tumor cells — bulk
leukemia cells that can be killed
by TKI drugs, and a subset of cells called
leukemia stem cells, which are resistant to TKIs and to
chemotherapy.
CT - 011, developed
by Israel - based Curetech Ltd, is also being tested in phase II trials in metastatic melanoma, colorectal cancer in combination with
chemotherapy, advanced renal cell and prostate cancers, as well as in acute myeloid
leukemia.
A trailblazing oncologist who took on childhood
leukemia by introducing combination
chemotherapy — in which anticancer drugs are given simultaneously rather than singly — retired in September after 50 years at MD Anderson.
Measuring the concentration of
leukemia cells in patient bone marrow during the first 46 days of
chemotherapy should help boost survival of young
leukemia patients
by better matching patients with the right intensity of
chemotherapy.