Sentences with phrase «leukemia cells in a lab»

Bradner's team showed that an existing TRIM24 binder can be used to make a TRIM24 protein degrader, which was able to take down leukemia cells in the lab.

A group of researchers at the Baylor College of Medicine has published the results of a study in the journal PLoS ONE demonstrating that a concentrated form of the compound sulforaphane found in broccoli and other cruciferous vegetables has been shown to reduce the number of acute lymphoblastic leukemia cells in a lab setting.

Not exact matches

In an attempt to answer this question, the researchers undertook a targeted manipulation of leukemia cell DNA in the laIn an attempt to answer this question, the researchers undertook a targeted manipulation of leukemia cell DNA in the lain the lab.

For the past several years, researchers have been modifying T cells so they can attack leukemia, but the cells must be painstakingly isolated from the patients themselves and grown in a lab.

«In my lab we've seen a direct interaction between fat cells and leukemia cells that may help explain this increased risk of disease relapse,» said Steven Mittelman, MD, PhD, director of the Diabetes and Obesity program at CHLA and senior author on the study.

While testing that idea, the researchers noticed something peculiar about cancerous cells that had been removed from leukemia patients and were growing in lab dishes.

Hungerford, a predoctoral fellow, was writing his doctoral thesis on chromosomes in a genetics lab at Fox Chase Cancer Center, and detected a tiny flaw in chromosomes from the blood cells of patients with a type of leukemia.

The lab chose to use the TCL1 mouse model to study B - cell leukemia because ~ 90 percent of human chronic lymphocytic leukemia (CLL) patients express the TCL1 protein, and the overexpression of TCL1 in B cells leads to the development of CLL in mice.

The lab further developed inhibitors to target the expression of XBP - 1 and established that blocking the expression of XBP - 1 by specific small - molecule chemical inhibitors can stall malignant progression of leukemia in mice and induce apoptosis in primary human leukemic cells.

Inspired by XBP - 1's roles in maintaining a homeostatic ER, the lab began to examine the role of XBP - 1 in B - cell leukemia whose progression does not require dramatic ER expansion like that in multiple myeloma.

And a compound in avocados called avocatin B can kill leukemia cells, according to a lab study.