Telomerase reverse transcriptase promoter mutations can cause high -
level reactivation of the telomerase enzyme in bladder cancer.
Not exact matches
In the samples studied by the scientists, there are also high
levels of atmospheric contamination from lead during the Roman Empire, when large quantities of this metal were extracted in the south of the Iberian Peninsula, as well as during the past 300 years, coinciding with the Industrial Revolution and the
reactivation of mining activity in southern Spain.
To determine whether the
reactivation of methylation - silenced genes by EGCG is a general phenomenon that also occurs in other cell lines, we studied the effects of EGCG treatment on the methylation status and mRNA
levels of p16INK4a or RARβ in three other human cancer cell lines (Fig. 3C) ⇓.
They also discovered that the latency type and
levels of spontaneous
reactivation indicated how effectively chemotherapy drugs reactivated the virus.
In fact, some noise enhancers doubled
reactivation levels when combined with activators.
In a study of overweight but otherwise healthy people, those with loneliness showed higher
levels of inflammation when faced with stressful activities; another set of subjects experienced more inflammation, pain, depression and fatigue than normal, plus a
reactivation of dormant viruses in the body.
If virus neutralizing antibody
levels are high at the item of
reactivation, immune complexes may be formed.