Sentences with phrase «levels at time points»

BCR - ABL1 transcript levels at time points within the first year of therapy for CML can best predict the achievement of a deep molecular response.

Not exact matches

It is important to note that while these are the levels we are focused on hitting and we have plans in place to achieve them, our prior experience on the Model 3 ramp has demonstrated the difficulty of accurately forecasting specific production rates at specific points in time.

A smartphone app also connects to a SIM card embedded in the car and lets the driver see their charge level at any point in time.

In this study, the effects of sea level rise (assumed to continue at present, at the time of the study, rates, which the authors noted was likely conservative), wave fetch, wind speed and direction were examined and the resultant erosion rate was estimated for the Western and Eastern shore of Uppands, Port Isobel and Tangier Island by selecting 10 points along the western and eastern shoreline of all the islands.

At that time, we said of SPDR Gold Trust ($ GLD) that a bounce into new resistance of its prior support level (around the $ 150 area) would provide an ideal, low - risk short selling entry point.

At this point there are two situations: either you use a bot - builder and you will have a hard time going to this level of customization.

If the speculative bubbles and crashes across market history have taught us anything (particularly the repeated episodes of recklessness we've observed over the past two decades), it's this: regardless of the level of valuation at any point in time, we have to allow for the potential for investors to adopt a psychological preference toward risk - seeking speculation, and no amount of reason will dissuade them even when that speculation has already made a collapse inevitable over a longer horizon.

The level of intermediaries» interest rates for households and small businesses remains historically low — in particular, notwithstanding the fact that the cash rate exceeds by 1.5 percentage points its level at the previous cyclical trough in 1993/94, rates paid by borrowers, especially for housing, typically remain below their level at that time.

Although Butterfly Labs does not have the best reputation right now, they were beloved in the Bitcoin community at this particular point in time due to their dedication to taking Bitcoin mining to the next level.

The 10 - year swap spread in the United States, for example, has increased in 2000 by about 50 basis points, to a level higher than at the time of disruptions in markets during the LTCM crisis in 1998.

Dow reaches new milestone One thousand points isn't what it used to be, accounting for a move of less than 5 % at present levels, but markets took note of this week's milestone nonetheless as the venerable Dow Jones Industrial Average broke and closed above the 22,000 mark for the first time.

Indeed, because the level of interest rates at any point in time is highly correlated with the level of nominal economic growth over the preceding decade, the relationship between starting valuations and actual subsequent S&P 500 nominal total returns is nearly independent of interest rates.

These differences point to the difficulty of making fine judgments about the level of real interest rates at a given point in time.

Therefore there is not question of legitimacy at any level or point in time.

Since «persons» are regarded by Hartshorne as «low - level universals» expressed by the total temporary state of whatever it is that constitutes a «momentary self» at any particular point in time, it follows that the word «person,» quite unlike the word «symphony,» does not simply refer to the completed totality of this or that particular series of the total life - span of that particular series of «momentary selves.»

You may consider this point to be moving, but that, of course, brings in time at another level.

Yet at certain other points he did definitely lift the position of women to a considerably higher level than that current in Arabia before his own time.

Even on the most basic, day - to - day level, we were created with personal tipping points — an awareness that we're inching closer to becoming burned out at work, or hurt one too many times by a friend or family member.

«It's prejudice, and it's ignorance, on a level that is staggering at this point in time.

At some point, a mom's productivity level and quality will greatly decrease if she does not get time to re-charge.

Pour contents into a 8 x 12 ″, or similarly sized, pan / Carefully place in a secure, level spot in the freezer / Freeze for 1 — 2 hours / Remove from freezer and scrape, smash and stir mixture with a fork, breaking into small icey bits / Return to the freezer and repeat this process three more times, every 30 minutes / Granita should be done at this point, coarse bits of ice, about like a snow cone / Place granita in container, cover and freeze until ready to use.

The level has been on and off the rim at least three times at this point while Kyle Lowry is directing traffic like the All - Star point guard he is.

We've mentioned it several times at this point but the group is playing at a much higher level than a Team 3 games below.500 and a huge reason for that is needs to be All Star Nate Johnson.

the last time i checked, 72 points doesn't guarantee Top 4 place......... Lem me explain...... What if there are 4 teams levelled at 72?

These young guns will only get a chance to prove themselves at top level if and only if arsenal make massive signings that will give us a major trophy... if we are for example leading the league in like seven points in February, then we can afford to give them some minutes on field but they wont get game time on the current team cz the manager realizes that the club needs trophies and hez running out of time so i even doubt he will use them in capital one cup... Good luck boys

nice to see you crawl out of your hole just in time to offer your 2 cents worth once again... unlike yourself I started following this team long before Wenger arrived on the scene and will continue to do so long after he's gone... in his earlier years I admired the cerebral elements he brought to the EPL, which at that point was more brutish than beautiful, and I respected the seemingly tireless efforts of Arsene, Dein & staff to uncover and develop talent without sacrificing the product on the field... likewise I appreciated that such a youthful manager wasn't afraid to bring strong personalities and / or world - class players into the fold without being fearful of how said players would potentially undermine and / or dilute his authority... unfortunately this all changed about 10 years ago and culminated in the removal of all our greatest players, both young and old, without any real replacements coming in... from Henry to RVP to Fabergas and Nasri, it was easy to see that this club was no longer interested in competing at the highest levels... instead of being honest, minus the ridiculous claims regarding the new stadium, Wenger chose to side with management and in doing so became the «front man» for this corporation pretending to be a world - class soccer club... without the «front man» this organization would have been exposed numerous years earlier, so his presence was imperative if the facade was to continue... it's for this reason and more that I despise what this once great man and Kroenke has done to my beloved club... the gutless, shameful and manipulative way they have treated the fans, like myself, is largely indefensible and this is why I felt it necessary to start offering my opinion in a public format... trust me, I resisted the temptation for many years but as long as the same shit continues to exist I will voice my opinions and if you don't like it maybe you should look for a different team to pretend to follow

Let's face it goalkeepers tend to march to the beat of a different drum and Szczesny certainly fell into that category, but most of his antics were relatively harmless and simply reflected a certain level of immaturity that isn't uncommon for someone thrust into the limelight at such a young age... lord knows we've seen that happen with numerous players throughout the years and very few were ever banished for such behaviour... the only on - field action that drove me crazy was his inability to take a deep breath and not try to rush the play with an ill - timed throw at certain points in the game when common sense suggested holding the ball and slowing things down... the fact that he continued to do this probably had a lot to do with the glaring lack of coaching time spent with the goalkeepers... ultimately he made the fateful decision to take his frustrations out into the public sphere and paid dearly for it... in the end, his services were wanted by several of the best Italian squads, which is significant considering the historical importance placed on the defensive side of the ball in Serie A... all I know is that if someone asked me to pick the most athletically gifted goalkeeper we have had in our squad since the arrival of Wenger, without hesitation, he would be my pick and for that reason his departure is more than a little disappointing... what else is new though

why was Sanchez truly playing... no one believes he was too injured to play to start the season, and some like myself would go as far to suggest he wasn't injured at all... so why play him... they can't say it was to appease the fans because when was that ever a factor at this club except when «panic buys» were in the offing... I believe that this was to give Arsenal a little leverage when it comes to negotiating his transfer... just imagine their horrible bargaining position if Sanchez never saw the field before the deadline then heading back to South America and played for Chile... regardless of the facts, this was sadly again another example of a team putting business ahead of fielding a team with the greatest chance to secure 3 points... of course, some will say that Sanchez is, or was, our best player, so obviously he's a no - brainer to start, but those who really watch the game know that his heart hasn't been truly in it for quite some time... even at the end of last season you could see a definitive difference between the Sanchez who played for Chile and the one that played for Arsenal... that being said, 70 % of Sanchez is still better than a 100 % of the vast majority of our remaining roster... shame on you Arsene and shame on you too Sanchez for that telling smirk... I've supported your attempt to push this squad to the next level but don't pretend for a second that you didn't know you were being watched... don't lower your standards or you'll end up like this club, on the outside looking in

It makes sense from Arsenal's point of view if Holding and Chambers can get game time together in central defence for England at any level, weather they are the future for England and Arsenal depends on how good they can become.

At this point, Bob Stoops is the Arsene Wenger of college football — he succeeded so quickly that maintaining a high level, but not the highest level, has at times given the impression of tailing ofAt this point, Bob Stoops is the Arsene Wenger of college football — he succeeded so quickly that maintaining a high level, but not the highest level, has at times given the impression of tailing ofat times given the impression of tailing off.

Because this club is in a right mess at the moment and I can't imagine anyone on the international level joining us at this point in time.

stop making up stuff; by the time our injuries were at a normal level we were out of the race already and from that point onward we had the best form in the league equal to Chelsea.

We still lost away to Chelsea, lucky to leave Anfield with a point, Spurs took 4 points off of us, Utd beat us AT HOME and I have know idea who's turning up at Old Trafford... I feel now we REALLY need to hold unto 3rd and most importantly the players shouldn't be forgotten either, they get paid more than most people will see in their lifetime... The should be performing at the highest level on a constant basis but sadly they haven't either at least in the games that really count... I love Arsenal but something has to give in order for is to proceed and I want to see that Arsenal again at least one last time.AT HOME and I have know idea who's turning up at Old Trafford... I feel now we REALLY need to hold unto 3rd and most importantly the players shouldn't be forgotten either, they get paid more than most people will see in their lifetime... The should be performing at the highest level on a constant basis but sadly they haven't either at least in the games that really count... I love Arsenal but something has to give in order for is to proceed and I want to see that Arsenal again at least one last time.at Old Trafford... I feel now we REALLY need to hold unto 3rd and most importantly the players shouldn't be forgotten either, they get paid more than most people will see in their lifetime... The should be performing at the highest level on a constant basis but sadly they haven't either at least in the games that really count... I love Arsenal but something has to give in order for is to proceed and I want to see that Arsenal again at least one last time.at the highest level on a constant basis but sadly they haven't either at least in the games that really count... I love Arsenal but something has to give in order for is to proceed and I want to see that Arsenal again at least one last time.at least in the games that really count... I love Arsenal but something has to give in order for is to proceed and I want to see that Arsenal again at least one last time.at least one last time...

But they were forced to work hard for the three points, as Steve Bruce's side battled back from conceding two early goals to go in at half - time level.

We improved and made some chances, shooting two times against the bar, but it's not enough for us to win some points today and it's not enough at this level when we have important dreams and thinking about the important things we want to do this season.»

«There was a space and time for everyone to think, to feel, to decide and, from his point of view, he made the decision to still want to play football at the highest level.

Reaction: De Bruyne is my Man City blueprint — Guardiola (Premier League) Report: De Bruyne makes it sweet 16 for awesome Man City (Premier League) Report: Otamendi wins derby to fire Man City 11 points clear (Premier League) Reaction: Klopp calls for Liverpool focus after Euro spree (Champions League) Report: «Fab Four» fire seven - goal Liverpool into last 16 (Champions League) Reaction: Mourinho pledges only «the truth» on injuries (Champions League) Report: Lukaku and Rashford send Man United into last 16 (Champions League) Reaction: Mourinho wants new shooting boots for Lukaku (Premier League) Report: Old boy Young downs Watford to lift Man United (Premier League) Reaction: Klopp looks on bright side after Chelsea draw (Premier League) Report: Willian denies Liverpool morale - boosting win (Premier League) Reaction: Guardiola targets Champions League milestone (Champions League) Report: Sterling strikes late to earn Man City top spot (Champions League) Report: Young England stifle Neymar's Brazil (friendly) Reaction: Loftus - Cheek showed he can cut it — Southgate (friendly) Report: New boys impress as England hold Germany (friendly) Reaction: Mourinho defends lack of Lukaku charity (Champions League) Report: Hapless Svilar helps Man Utd to brink of last 16 (Champions League) Reaction: «Stand up and be counted», Klopp tells Liverpool (Premier League) Report: Spurs» Kane rips sorry Liverpool to shreds (Premier League) Reaction: Guardiola proud to beat «best opponents» Napoli (Champions League) Report: Jesus earns Man City narrow win over Napoli (Champions League) Reaction: Mourinho and Klopp at odds over Anfield stalemate (Premier League) Report: Man Utd held at Liverpool as Mourinho parks the bus (Premier League) Report: McClean breaks Welsh hearts as Ireland reach play - offs (2018 World Cup) Reaction: Southgate admits England have long way to go (2018 World Cup) Report: Kane sends lacklustre England to World Cup (2018 World Cup) Reaction: Man City's show of force thrills Guardiola (Champions League) Report: Chelsea old boy De Bruyne gives Man City crucial win (Champions League) Reaction: «Amazing» Lukaku won't lose focus — Mourinho (Champions League) Report: Lukaku and Martial lead Man United in CSKA rout (Champions League) Reaction: Klopp says Liverpool on track despite stalemate (Champions League) Report: Coutinho scores as Liverpool held in Moscow (Champions League) Reaction: Man United part of «second level», says Mourinho (Champions League) Report: Fix - it Fellaini gets Man United off the mark (Champions League) Reaction: De Bruyne masterclass leaves Guardiola purring (Premier League) Report: Mané sent off as five - star Man City crush Liverpool (Premier League) Reaction: Alli gesture takes shine off England win (2018 World Cup) Report: Rashford redemption sends England closer to Russia (2018 World Cup) Reaction: Klopp hopes Euro progress yields transfer lift (Champions League) Report: Can brace gets Liverpool back into big time (Champions League) Report: Sterling rescue act spares 10 - man Man City (Premier League) Reaction: Conte happy for Chelsea to play the hunters (Premier League) Report: Alonso ruins Spurs» Wembley house - warming (Premier League) Report: Lukaku double fires Man United to winning start (Premier League) Reaction: Wenger lauds Giroud after Arsenal edge Leicester (Premier League) Report: Giroud earns Arsenal madcap opening win (Premier League) Reaction: Wenger fearful of another slow Arsenal start (Community Shield) Report: Courtois and Morata gift Arsenal victory at Wembley (Community Shield)

Maribor come to Anfield in a fortnight's time and the Reds will be looking to take full advantage in an unpredictable group, hoping to ease the pressure at the top with Spartak Moscow breathing down their necks level on points in second place.

Ligali was at a point in time under consideration by former Super Eagles coach Sunday Oliseh but the move didn't materialise and the 25 year old who has already represented France at youth level will be hoping to make the step up to the senior team in the future.

Didier Drogba's goal to level the match at 2 - 2 wasn't praised by very many of his peers, as opposed to Terry's equaliser, while at the full - time whistle both Drogba and Terry were involved in a heated discussion regarding Villa's late equaliser, with Drogba clearly pointing the finger at the Chelsea skipper.

That speech was a big turning point for Geoff's project — for the first time, a viable presidential candidate was talking about building on his work in a big way, at the national level.

The problem is that NOCSAE's decision could not have come at a worse time (or perfect time, I guess, depending on your point of view): just as football teams, from the youth level to the National Football League, are gearing up for the fall season.

Look, at some point, we have all been this mom, especially new, first - time parents, but Worrying Mom takes it to another level.

The ultra padded seats offer superior comfort and the padded 5 point harness makes sure your baby is secure at all times, while maintaining the comfort level;

At the back of car seat the harness and headhugger can easily be adjusted, at the same time, to ensure that the three - point safety harness stays at the correct height level as your baby growAt the back of car seat the harness and headhugger can easily be adjusted, at the same time, to ensure that the three - point safety harness stays at the correct height level as your baby growat the same time, to ensure that the three - point safety harness stays at the correct height level as your baby growat the correct height level as your baby grows.

An important point to note is that the concept of a country is fairly new; I have read, and agree, that modern states did not become such an important unit of human organization until the Great Depression in the 1930s; at that time the problems facing them - broken economies and socialist movements - the country level government was the only organization existing that could solve these problems while the existing power structure stayed in power.

In a Facebook post, Wilson said he realizes that a campaign for governor «would be a 24/7 endeavor through Election Day,» and he says «This is a level of family time and commitment that would not be possible at any point during the campaign, in my first year in office and perhaps not at all throughout my time as governor.»

«I think he was simply pointing out that the world is a dangerous place, the level of threat is increasing and the police can not be everywhere at all times,» said Schirmer.

``... As the New York Times has pointed out, my budget plan is at the center of the campaign: «After leveling a barrage of attacks against the proposal put forth by Mr. Ryan, the Democratic candidate Kathy Hochul, has tightened the race considerably...»»

There were clear differences in the composition of immune cells in the wounds and the immune cells present produced higher levels of TGFß at earlier time points.