Reduced cholesterol
levels decrease your risk for heart disease.
He also observed that using interventions to lower homocysteine
levels decreased this risk.
Not exact matches
These
risks and uncertainties include: Gilead's ability to achieve its anticipated full year 2018 financial results; Gilead's ability to sustain growth in revenues for its antiviral and other programs; the
risk that private and public payers may be reluctant to provide, or continue to provide, coverage or reimbursement for new products, including Vosevi, Yescarta, Epclusa, Harvoni, Genvoya, Odefsey, Descovy, Biktarvy and Vemlidy ®; austerity measures in European countries that may increase the amount of discount required on Gilead's products; an increase in discounts, chargebacks and rebates due to ongoing contracts and future negotiations with commercial and government payers; a larger than anticipated shift in payer mix to more highly discounted payer segments and geographic regions and
decreases in treatment duration; availability of funding for state AIDS Drug Assistance Programs (ADAPs); continued fluctuations in ADAP purchases driven by federal and state grant cycles which may not mirror patient demand and may cause fluctuations in Gilead's earnings; market share and price erosion caused by the introduction of generic versions of Viread and Truvada, an uncertain global macroeconomic environment; and potential amendments to the Affordable Care Act or other government action that could have the effect of lowering prices or reducing the number of insured patients; the possibility of unfavorable results from clinical trials involving investigational compounds; Gilead's ability to initiate clinical trials in its currently anticipated timeframes; the
levels of inventory held by wholesalers and retailers which may cause fluctuations in Gilead's earnings; Kite's ability to develop and commercialize cell therapies utilizing the zinc finger nuclease technology platform and realize the benefits of the Sangamo partnership; Gilead's ability to submit new drug applications for new product candidates in the timelines currently anticipated; Gilead's ability to receive regulatory approvals in a timely manner or at all, for new and current products, including Biktarvy; Gilead's ability to successfully commercialize its products, including Biktarvy; the
risk that physicians and patients may not see advantages of these products over other therapies and may therefore be reluctant to prescribe the products; Gilead's ability to successfully develop its hematology / oncology and inflammation / respiratory programs; safety and efficacy data from clinical studies may not warrant further development of Gilead's product candidates, including GS - 9620 and Yescarta in combination with Pfizer's utomilumab; Gilead's ability to pay dividends or complete its share repurchase program due to changes in its stock price, corporate or other market conditions; fluctuations in the foreign exchange rate of the U.S. dollar that may cause an unfavorable foreign currency exchange impact on Gilead's future revenues and pre-tax earnings; and other
risks identified from time to time in Gilead's reports filed with the U.S. Securities and Exchange Commission (the SEC).
Risk management basically involves decreasing your SPY exposure until you hit your desired risk lev
Risk management basically involves
decreasing your SPY exposure until you hit your desired
risk lev
risk levels.
Decrease your
level of exposed
risk to underwriters by going through Investopedia Acadaemy's Master Your Money course.
We believe that a policy of portfolio concentration may well
decrease risk if it raises, as it should, both the intensity with which an investor thinks about a business and the comfort -
level he must feel with its economic characteristics before buying into it.»
They use a conventional glide path, which gradually
decreases the allocation to equities with age to a constant after retirement, to determine target
risk levels over the life cycle.
Examples of these
risks, uncertainties and other factors include, but are not limited to the impact of: adverse general economic and related factors, such as fluctuating or increasing
levels of unemployment, underemployment and the volatility of fuel prices, declines in the securities and real estate markets, and perceptions of these conditions that
decrease the
level of disposable income of consumers or consumer confidence; adverse events impacting the security of travel, such as terrorist acts, armed conflict and threats thereof, acts of piracy, and other international events; the
risks and increased costs associated with operating internationally; our expansion into and investments in new markets; breaches in data security or other disturbances to our information technology and other networks; the spread of epidemics and viral outbreaks; adverse incidents involving cruise ships; changes in fuel prices and / or other cruise operating costs; any impairment of our tradenames or goodwill; our hedging strategies; our inability to obtain adequate insurance coverage; our substantial indebtedness, including the ability to raise additional capital to fund our operations, and to generate the necessary amount of cash to service our existing debt; restrictions in the agreements governing our indebtedness that limit our flexibility in operating our business; the significant portion of our assets pledged as collateral under our existing debt agreements and the ability of our creditors to accelerate the repayment of our indebtedness; volatility and disruptions in the global credit and financial markets, which may adversely affect our ability to borrow and could increase our counterparty credit
risks, including those under our credit facilities, derivatives, contingent obligations, insurance contracts and new ship progress payment guarantees; fluctuations in foreign currency exchange rates; overcapacity in key markets or globally; our inability to recruit or retain qualified personnel or the loss of key personnel; future changes relating to how external distribution channels sell and market our cruises; our reliance on third parties to provide hotel management services to certain ships and certain other services; delays in our shipbuilding program and ship repairs, maintenance and refurbishments; future increases in the price of, or major changes or reduction in, commercial airline services; seasonal variations in passenger fare rates and occupancy
levels at different times of the year; our ability to keep pace with developments in technology; amendments to our collective bargaining agreements for crew members and other employee relation issues; the continued availability of attractive port destinations; pending or threatened litigation, investigations and enforcement actions; changes involving the tax and environmental regulatory regimes in which we operate; and other factors set forth under «
Risk Factors» in our most recently filed Annual Report on Form 10 - K and subsequent filings by the Company with the Securities and Exchange Commission.
The Governing Council judges that the
risks to the Canadian financial system have
decreased somewhat relative to the December FSR, but that the overall
level of
risk remains high.
Yes, there are many dietary and environmental factors that affect breast cancer
risk, most of which are presumed to act via increasing or
decreasing the
levels of estrogens or estrogen - like substances to which women are chronically exposed.
Most large studies have found only a very small
decrease in
risk of colon cancer with the consumption of higher
levels of dietary fiber and no
decrease in
risk of colon cancer recurrence, according to the University of Maryland Medical Center.
This recipe is full of chickpeas which help promote bone health, improve blood sugar
levels in diabetics, improve blood pressure, promote heart health, reduce bad cholesterol, and reduce
risks of cancer and
decreases tumor growth rates.
The high
levels of antioxidants in collard greens have been linked to a
decreased risk of developing prostate cancer (25).
Finally, we have reviewed a large - scale study on high blood pressure showing an association between high
levels of protein intake (in the vicinity of 100 grams per day) and significantly
decreased risk of high blood pressure over an 11 - year period of time.
Onions have been shown to lower blood sugar
levels in several animal and human studies and may
decrease the
risk of diabetes.
According to the American Heart Association, mono and polyunsaturated fats, when consumed in moderation and eaten in place of saturated or trans fat, can help reduce blood cholesterol
levels and
decrease risk for heart disease.
Lower
levels of the hunger hormone ghrelin and
decrease your
risk of heart disease and kidney disease.
Hemp seeds also contain high
levels of vitamin E, which will
decrease inflammation in the body lowering your
risk of cancer and heart disease as well as ease pain from arthritis.
Medium - chain triglycerides: Scientific literature review investigating the potential of medium chain triglycerides and medium chain fatty acids (found in virgin coconut oil) for increasing thermogenesis,
decreasing body fat, reducing
risk of cardiovascular disease, stabilizing insulin
levels for people with diabetes type 2, reversing intestinal inflammation, and protecting the liver from hepatotoxicity
Those that had ate the highest
levels of CLAs experienced a 36 percent
decrease in their
risk of developing heart disease.
Mono and polyunsaturated fats, when consumed in moderation and eaten in place of saturated or trans fats, can help reduce blood cholesterol
levels and
decrease risk for heart disease.
Monounsaturated fats can improve blood cholesterol
levels,
decrease your
risk of heart disease, and can help regulate blood sugars
levels.
Likewise, as the number of
risk factors for exertional heat illness increases, the maximum environmental heat and humidity
level for safe exercise, sports participation, or other physical activities will
decrease.
Baby Center noted that oxytocin can even help reduce your
risk of developing postpartum depression,
decrease your stress
levels, and make you feel happier.
Combine this with the benefits for mother —
decreased risk of postpartum depression, increased milk production, increased pain tolerance, and reduced postpartum bleeding, cortisol
levels and blood pressure — and skin - to - skin contact looks to be an incredibly important part of newborn care!
For example, one hundred percent of an apple's quercetin (an antioxidant that has been linked to lower inflammation
levels as well as
decreased risk of prostate and lung cancers) content is in its skin!
If a woman is past her due date by two weeks or more, she may be at
risk for low amniotic fluid
levels since fluids can
decrease by half once she reaches 42 weeks gestation.
Students enrolled in NutriBullet University have seen a variety of health improvements such as a
decrease in total cholesterol
levels, improved cognitive function and a
decreased risk for lifestyle diseases.
Breastfeeding may
decrease the
risk of cardiovascular disease in later life, as indicated by lower cholesterol and C - reactive protein
levels in breastfed adult women.
That might help tease out some of the questions about whether the pitocin is causing the depression or merely being used in women who have
decreased oxytocin
levels or receptors to help with labor progress, who also happen to be at
risk for depression.
Despite a 56 %
decrease in the national incidence of sudden infant death syndrome (SIDS) from 1.2 deaths per 1000 live births in 19921 to 0.53 death per 1000 live births in 2003,2 SIDS continues to be the leading cause of postneonatal mortality in the United States.3 The
decreased rate of SIDS is largely attributed to the increased use of the supine sleep position after the introduction of the «Back to Sleep» campaign in 1994.4 - 7 More recently, it has been suggested that the
decrease in the SIDS rate has
leveled off coincident with a plateau in the uptake of the supine sleep position.8 Although caretakers should continue to be encouraged to place infants on their backs to sleep, other potentially modifiable
risk factors in the sleep environment should be examined to promote further decline in the rate of SIDS.
Doing so increases the heat
level and
decreases the oxygen
level under that blanket, and both are increased
risks for Sudden Infant Death Syndrome (SIDS).
Thus, stress or pain, which may be associated with breastfeeding, may result in a
decrease in serotonin
levels with resultant anxiety and depression.15 Early identification of at -
risk women is important to both
decrease the negative sequelae of postpartum depression and, potentially, to increase breastfeeding success.
The most recent study report described in these same regions
decreased tissue
levels of 5 - HT and tryptophan hydroxylase, the synthesizing enzyme for serotonin, and no evidence of excessive serotonin degradation as assessed by
levels of 5 - hydroxyindoleacetic acid (the main metabolite of serotonin) or ratios of 5 - hydroxyindoleacetic acid to serotonin.30 A recent article described a significant association between a
decrease in medullary 5 - HT1A receptor immunoreactivity and specific SIDS
risk factors, including tobacco smoking.40 These data confirm results from earlier studies in humans39, 41 and are also consistent with studies in piglets that revealed that postnatal exposure to nicotine
decreases medullary 5 - HT1A receptor immunoreactivity.42 Animal studies have revealed that serotonergic neurons located in the medullary raphe and adjacent paragigantocellularis lateralis play important roles in many autonomic functions including the control of respiration, blood pressure, heart rate, thermoregulation, sleep and arousal, and upper airway patency.
Declines in VA acuity over time were associated with increased mortality
risk in part because of
decreasing levels of IADL over time.
While elevated
levels of vitamin D have been associated with a
decreased risk of MS in adulthood, some previous research also has suggested that vitamin D exposure in utero may be a
risk factor for MS in later life.
A
decrease in the amount of time spent eating and an increase in overnight fasting reduces glucose
levels and may reduce the
risk of breast cancer among women, report University of California, San Diego School of Medicine researchers in the journal Cancer Epidemiology, Biomarkers & Prevention.
«We found that higher
levels of detection were associated with a
decreased subsequent
risk of cancer,» said Douglas A. Corley, MD, PhD, a gastroenterologist and research scientist with the Kaiser Permanente Division of Research.
This study is the first to show that higher childhood vitamin D
levels are significantly associated with a
decreased risk of IA.
«Current
levels of radiation shielding would, at best, modestly
decrease the exposure
risks.»
However, increases in some
risk factors, such as rising
levels of obesity, suggest that these
decreasing trends may be in danger of reversing.»
Though inflammation
decreased as blood
levels of those fatty acids rose, higher
levels of oleic acid or long - chain omega - 3s did not appear to have any relationship to body composition or signs of
decreased diabetes
risk despite longstanding recommendations that people eat more of these «healthy» fats.
C - reactive protein
levels, a
risk factor for heart disease and other illnesses,
decreased in both the low - carb and Mediterranean, but not in the low - fat.
In the new study, every unit increase in vitamin D
level after supplementation of the vitamin
decreased the
risk of progression to diabetes by 8 percent, the authors reported.
In persons with
decreasing hs - cTnT
levels (e.g., 6 - year reductions > 50 percent from baseline), there was also evidence suggestive of lower
risk for outcomes compared with persons with stable or increasing concentrations.
«Indeed, even a low
level of PA such as walking a minimum of 2 hours per week has been associated with
decreased risk of hospitalization for exacerbated COPD.»
Our study, along with prior studies, supports the notion that «cognitive reserve» resulting from early - life and lifelong education and cognitive stimulation may be a potent strategy for the primary prevention of dementia in both high - and low - income countries around the world.21 However, it should be noted that the relationships among education, brain biology, and cognitive function are complex and likely multidirectional; for instance, a number of recent population - based studies have shown genetic links with
level of educational attainment, 22,23 and with the
risk for cognitive decline in later life.24 Higher
levels of educational attainment are also associated with health behaviors (eg, physical activity, diet, and smoking), more cognitively - complex occupations, and better access to health care, all of which may play a role in
decreasing lifetime dementia
risk.
Rising
levels of education among US adults over the past 25 years may also have contributed to
decreased dementia
risk.
Other researchers have identified another factor that could contribute to a correlation between bilingualism and a
decreased risk of dementia — the higher education
level that is present in some people who speak more than one language.
Elevated plasma TG
levels represent a
risk factor for CVD in humans, and an adjusted analysis of patients in the Framingham Heart Study suggests that each
decrease of 1 mg / dl in plasma ApoC - III
levels is associated with a 4 %
decrease in CVD
risk (11), further supporting the potential therapeutic benefit of suppressing plasma ApoC - III
levels in humans to reduce CVD.