Sentences with phrase «levels in embryonic stem cells»

To determine whether huntingtin is involved in trafficking a specific subset of proteins, we measured changes in global transcription levels in embryonic stem cells and neurons lacking huntingtin.

Not exact matches

This study provides experimental evidence which shows the important role of RNA levels in the controlling the fate of embryonic stem cells, and shows an understanding of RNA's ability to differentiate stem cells at the molecular level.

«Global levels of DNA methylation in IPS cells look amazingly similar to embryonic stem cells,» Ecker says, «but there are distinct regions that do not get reprogrammed properly.»

mRNA expression from the targeted allele could be detected in embryonic stem cells by RT - PCR (Figure 1D), although expression was reduced approximately 5-fold relative to wt mRNA transcript levels as determined by Northern blotting of RNA from the testis of heterozygous animals (Figure 1E).

One caveat is that the authors also observed that one of the eight human embryonic stem cell lines established following spindle transfer showed a drift in mitochondrial heteroplasmy in a subset of stem cells, despite low levels of carryover detected in the embryo.

10/10/2007 Researchers Reveal Repressor Protein Blocks Neural Stem Cell Development A protein known to repress gene transcription at the molecular level in a variety of processes also blocks embryonic neural stem cells from differentiating into neurons, according to a study by University of California, San Diego and Howard Hughes Me... MorStem Cell Development A protein known to repress gene transcription at the molecular level in a variety of processes also blocks embryonic neural stem cells from differentiating into neurons, according to a study by University of California, San Diego and Howard Hughes Me... Morstem cells from differentiating into neurons, according to a study by University of California, San Diego and Howard Hughes Me... More...