Sentences with phrase «levels than patients»

«Patients with persistent VPC asthma demonstrated higher disease burden, compromised lung function, and higher total and specific immunoglobin E levels than patients with non-persistent VPC asthma,» Haselkorn said.

Not exact matches

Intarcia has completed several late - stage clinical trials in which it uses the pump to deliver a glucose - controlling drug continuously for months — an idea, that if successful (and approved by the FDA) could significantly help patients with type 2 diabetes, fewer than half of whom maintain the recommended glycemic levels.

Amgen unveiled some promising news during the American Heart Association's annual meeting involving its next - gen cholesterol - busting medication Repatha, which has been shown to significantly reduce the level of «bad» cholesterol in patients, announcing that more than 60 % of patients who were receiving the therapy in a trial had a reduction in arterial plaque.

That's not just because of Opdivo's failure — last month, Keytruda was shown to be better than standard chemotherapy in untreated advanced lung cancer patients with high levels of the PD - L1 protein, both stopping cancer progression and extending patients» lives.

«More than twice the number of patients [were] still living at the end of the study after receiving IMAB362 plus chemotherapy compared to chemotherapy alone,» according to Ganymed CEO Özlem Türeci, with patients showing the highest level of that protein biomarker responding best to the treatment.

A California company called Dexcom connected a continuous glucose monitor (a device that had been around for more than a decade) wirelessly to a smartphone (or smart watch), allowing the user to read, plot, and share blood sugar levels with anyone, at five - minute intervals, all day long — and sending an alert when patients were at risk.

And he built on that concept on Thursday, announcing that his firm will bolster its patient assistance programs for more than 40 drugs, including by helping people who make up to four times the federal poverty level buy their treatments for free.

These risks and uncertainties include: Gilead's ability to achieve its anticipated full year 2018 financial results; Gilead's ability to sustain growth in revenues for its antiviral and other programs; the risk that private and public payers may be reluctant to provide, or continue to provide, coverage or reimbursement for new products, including Vosevi, Yescarta, Epclusa, Harvoni, Genvoya, Odefsey, Descovy, Biktarvy and Vemlidy ®; austerity measures in European countries that may increase the amount of discount required on Gilead's products; an increase in discounts, chargebacks and rebates due to ongoing contracts and future negotiations with commercial and government payers; a larger than anticipated shift in payer mix to more highly discounted payer segments and geographic regions and decreases in treatment duration; availability of funding for state AIDS Drug Assistance Programs (ADAPs); continued fluctuations in ADAP purchases driven by federal and state grant cycles which may not mirror patient demand and may cause fluctuations in Gilead's earnings; market share and price erosion caused by the introduction of generic versions of Viread and Truvada, an uncertain global macroeconomic environment; and potential amendments to the Affordable Care Act or other government action that could have the effect of lowering prices or reducing the number of insured patients; the possibility of unfavorable results from clinical trials involving investigational compounds; Gilead's ability to initiate clinical trials in its currently anticipated timeframes; the levels of inventory held by wholesalers and retailers which may cause fluctuations in Gilead's earnings; Kite's ability to develop and commercialize cell therapies utilizing the zinc finger nuclease technology platform and realize the benefits of the Sangamo partnership; Gilead's ability to submit new drug applications for new product candidates in the timelines currently anticipated; Gilead's ability to receive regulatory approvals in a timely manner or at all, for new and current products, including Biktarvy; Gilead's ability to successfully commercialize its products, including Biktarvy; the risk that physicians and patients may not see advantages of these products over other therapies and may therefore be reluctant to prescribe the products; Gilead's ability to successfully develop its hematology / oncology and inflammation / respiratory programs; safety and efficacy data from clinical studies may not warrant further development of Gilead's product candidates, including GS - 9620 and Yescarta in combination with Pfizer's utomilumab; Gilead's ability to pay dividends or complete its share repurchase program due to changes in its stock price, corporate or other market conditions; fluctuations in the foreign exchange rate of the U.S. dollar that may cause an unfavorable foreign currency exchange impact on Gilead's future revenues and pre-tax earnings; and other risks identified from time to time in Gilead's reports filed with the U.S. Securities and Exchange Commission (the SEC).

Earlier this year the company reported that patients who took PRX - 002 saw their alpha synuclein levels drop by as much as 96 %, which is a massive improvement that performed significantly better than a placebo.

In 2006, scientists evaluated the effects of vitamin D on the mental health of 80 elderly patients and found those with the lowest levels of vitamin D were 11 times more prone to be depressed than those who received healthy doses.

He must not be sold.He's also better than a lot of Chelsea youngsters.That's not enough basis for him to be sold.At top form he's better than Pedro, Moses and Willain.These are players whose main strength is dribbling and he tops them there no doubt.I remember him in one season having the highest dribble success rate percentage in the EPL.All he needs is to develop a level of consistency.A lot of their youngsters have potential but most won't be good as the Ox.The Ox himself has not reached full potential yet.He hasn't developed a certain level of consistency.Him also being a squad player is because of those above him.Those above him are all quality players.This won't be smart business at all.He's just going to destroy himself in another club and after being patient with him we are now deciding to sell him?

At 32 he won't be around for more than 3 years at the top level, so if Szczesny were to be patient and learn from the Czech, Arsenal could have two quality keepers on their hands.

«The level of psychosocial morbidity and suicidality associated with BPD is as great, or greater, than that experienced by patients with bipolar disorder,» said Zimmerman, director of outpatient psychiatry at Rhode Island Hospital and director of the Rhode Island Methods to Improve Diagnostic Assessment and Services (MIDAS) project.

The results of the study show that more than half of the patients with bipolar disorder who had elevated or low levels of cortisol in the blood, also had depression.

Twenty patients with kidney failure, for example, showed levels of ammonia and acetone more than 10 times that of healthy controls, and the researchers could watch those levels fall back to normal as the patients received dialysis treatment.

More than a decade ago while working at Johns Hopkins University School of Medicine, Rodriguez, an endocrinologist, questioned why patients with high HDL levels were still having heart attacks.

The current NCEP guidelines, published in 2001 and revised in 2004, recommend statins for heart disease patients with LDL («bad») cholesterol levels greater than 70 milligrams per deciliter of blood and for people who have a moderately elevated risk of heart disease as well as LDL levels above 100 mg / dL.

His lab differentiates iPSCs from autistic patients into neurons and glial cells, which they suspect may be releasing cytokines at levels higher than normal in autistic patients.

«Could there be a reason why heart disease patients or diabetics or even just obesity maybe would get exposed to higher levels of BPA than the rest of us?»

Patients of both types had protein levels in their joints that were significantly higher than individuals without joint disease.

Additionally, lung cancer patients who have high levels of YAP1 in their tumors are more likely to have a poorer prognosis than patients with low levels of YAP1.

«We found the FA patients had serum ApoA - I levels that were lower than healthy control subjects,» said senior author Ian Blair, PhD, a professor of Systems Pharmacology and Translational Therapeutics.

Eligible patients presented with tumor stages of T1c to T3a, prostate - specific androgen (PSA) levels of 20 or below, and one or two of three risk factors: stage T3a, a Gleason tumor score of seven or higher, or a PSA level greater than 10.

Primarily supported by a $ 5.6 million grant from the The Michael J. Fox Foundation for Parkinson's Research and conducted at 17 sites across the U.S., SURE - PD (Safety of URate Elevation in Parkinson's Disease) enrolled 75 recently diagnosed Parkinson disease patients with relatively low blood levels of urate (less than 6 mg / dL).

The largest urban health systems, which serve as safety nets for large patient populations with lower socioeconomic status and greater likelihood to speak English as a second language, do worse on government patient satisfaction scores than smaller, non-urban hospitals likely to serve white customers with higher education levels, according to a new study by Mount Sinai researchers published this month in the Journal of Hospital Medicine.

Of 32 patients participating in the trial, 11 had a partial response to the drug regimen, meaning a decrease in the extent of the cancer, and 53 had a very good partial response, meaning the level of certain myeloma - related proteins in the blood declines by more than 90 percent.

Patients with 2 or 3 of the predictors had a sudden cardiac death risk that was 145 times greater than patients with normal levels on all 3 mPatients with 2 or 3 of the predictors had a sudden cardiac death risk that was 145 times greater than patients with normal levels on all 3 mpatients with normal levels on all 3 measures.

More than 90 percent of Parkinson's patients report some level of olfactory dysfunction.

Koprowski says his group plans to investigate whether MS sufferers have lower uric acid levels than healthy people and whether gout patients have a lower MS incidence.

After 24 weeks, virus levels were undetectable — defined as less than 50 copies per milliliter of blood — in 62 percent of patients receiving TMC125, compared with 44 percent that received only the other drugs.

Researchers know that patients with several types of cancer, including prostate cancer, have higher than normal levels of a protein called AMACR, and that the protein is linked to the aggressiveness of the cancer.

When, for example, subjects were asked 20 times in succession to estimate the duration for which a square — displayed for exactly one second in each case — appeared on the screen, the estimates given by patients with schizophrenia exhibited a much higher level of variability than those of the control group.

In addition, 35 percent of patients with fructosamine levels higher than the cut - off, had no history of diabetes, indicating increased risks in patients who might not otherwise have been identified.

«Verbal aggression by patients linked with higher level of anger among mental health nurses than physical advances, new research shows.»

As expected, at one - year follow - up, patients on the statin drug had lower cholesterol and triglyceride levels than those on placebo.

GEx has been validated with 132 patients at three hospitals in Spain, Germany and the United Kingdom and, according to the tests performed, it provides better results than traditional rehabilitation programs, «This improvement is seen in the patient's functional capacity, as well as in weight loss and a reduction in cholesterol levels,» says Álvaro Martínez.

He said: «Information on outcome of patients with cut - off levels higher than in the current analysis would be of interest.

When human orbital fibroblasts from TED patient tissue were compared to tissue from patients without TED, the researchers discovered that TED orbital fibroblasts expressed higher levels of AHRs than non-TED orbital fibroblasts.

About 62 % of the patients had blood sugar levels less than 7 % and this did not differ across health status.

There was also a benefit found in patients with elevated progesterone levels prior to egg retrieval — and this was evident whether they were younger than 35 (47 % freeze - all vs 38 % fresh) or older than 35 (45 % freeze - all vs 30 % fresh).

In the malignant tissue, they found up to 1500 genes with mutations — a level higher than has been found for either lung cancer in smokers or skin cancer in patients with heavy exposure to ultraviolet radiation.

High - intensity exercise can help stable heart transplant patients reach higher levels of exercise capacity, and gain better control of their blood pressure than moderate intensity exercise, investigators report in a new study published in the American Journal of Transplantation.

Patients with sickle cell trait received about 13 % more of the medications used to treat anemia than other patients to reach the same level of hemPatients with sickle cell trait received about 13 % more of the medications used to treat anemia than other patients to reach the same level of hempatients to reach the same level of hemoglobin.

For more than half of those disorders, the women with PCOS had distress levels statistically similar to those of the female psychiatric patients.

In 12 heart attack patients, levels of 8 - epi PGF - 2 - were on average two and a half times higher than normal.

Patients with values lower than 10 mg / dl had a near two-fold increased rate of coronary atherosclerosis as compared with those showing normal levels.

Treatment of patients with thyrotropin levels at or below 10 mIU / L without symptoms may cause more harm than good and may represent overtreatment.

Prostate cancer patients whose tumour cells have high levels of this molecule are more than twice as likely to see their disease return following surgery.

All patients had iron deficiency, defined as a serum ferritin level of less than 100 ng / mL, or between 100 and 300 ng / mL if transferrin saturation [TSAT] was less than 20 %.

Using data from a large public brain tumor database called REMBRANDT, the researchers confirmed that patients with lower levels of SND1 survived longer than those with elevated SND1 expression.