When those cells were placed on a standard wound assay (for measuring properties
like cell migration and proliferation), they moved unusually fast.
Not exact matches
Like a free pass, its presence on the surface of lymphoma
cells facilitates their
migration through the vessel walls between adjacent endothelial
cells.
Researchers have uncovered a sieve -
like structure in lymph nodes that regulates the transport of proteins and
migration of white blood
cells into lymph nodes.
After injuries of healthy tissues, we would
like to accelerate the
migration of healthy
cells that move to close the wound.
Certain dot -
like structures, that are always located at the front of the
cell, adopt a crucial role in maintaining long term polarized
cell migration.
Kruppel -
like factor 4 (KLF4) is required for maintenance of breast cancer stem
cells and for
cell migration and invasion
Furthermore, many key steps,
like the development and
migration of primordial germ
cells to the gonads, happen within days or weeks of conception.
She has worked in prestigious Institutions
like the NIH - NCI, Bethesda, Md and the MIT, Cambridge, MA and developed an internationally recognised research profile in tumour
cell migration and invasion with over 65 publications and 2 patents to her name.
Like other chemokines, SDF - 1 binds to its receptors to promote directional
migration of
cells to specific locations (chemotaxis)[6 - 9].
They include its effects on endothelial
cell «differentiation» to yield tubular -
like structures, endothelial and tumor
cell proliferation, apoptosis, and
migration, as well as its effects on extracellular matrix remodelling enzyme activities of matrix metalloproteinase - 2 (MMP - 2) and urokinase - type plasminogen activator (uPA).