Now, as published in Science, Weizmann Institute scientists have created an artificial, network -
like cell system that is capable of reproducing the dynamic behavior of protein synthesis.
Not exact matches
Rather than an activator of T
cells, the molecule acted
like a brake, stopping the immune
system from its attack.
The theory of societies,
like modern general
systems theory, pictures a world made up of societies within societies (
systems within
systems) That is, societies do not just line up side by side
like mosaics — they form «nested hierarchies» that go from subatomic particles through
cells to animal bodies, or through stars to galaxies.
If human brains are
like body's
cells, there is a natural point of specialization, in which new
systems break away and form similar but slightly different branches, as
cells in a body become fingers, feet, hands, etc..
A single human egg
cell is alive, but it has no experiences
like those of an adult, or a child, or even of an animal with a central nervous
system.
Another possibility is that there was a reasonable probability of forming self reproducing
systems,
like cells, but that most of these forms of life did not evolve intelligence.»»
Like attempting to insert religion into the school
system, stymie medical research aka stem
cells, restrict a woman's reproductive rights... etc..
Waddington's paper in Towards a Theoretical Biology follows on from one by Brian Goodwin («A Statistical Mechanics of Temporal Organization in
Cells») in which Goodwin looks at the question of how ordered systems like cells, and still more macro-organisms, supervene on the movements of their constituent molecules, and how one is to close the gap between molecular biology and cell physio
Cells») in which Goodwin looks at the question of how ordered
systems like cells, and still more macro-organisms, supervene on the movements of their constituent molecules, and how one is to close the gap between molecular biology and cell physio
cells, and still more macro-organisms, supervene on the movements of their constituent molecules, and how one is to close the gap between molecular biology and
cell physiology.
Even if such study leads us to something comparatively unromantic or unexciting,
like «electrons, or the organic chemistry of the living
cell, or the autonomic nervous
system or the sun or anything else, then the workable idea of God would say: Lo, this is God.
Your developing baby doesn't look
like a baby yet, but
cells have clustered in places where your baby's heart and circulatory
system will grow as well as where lungs, urinary tract, intestines, brain and entire nervous
system will grow.
Eager to sort through the pile of curriculum vitae's on his desk, Rudnicki is particularly looking for molecular geneticists working on different stem
cell systems; scientists with genomics bents
like proteomics, microarray analysis, and bioinformatics; and a couple of clinician scientists.
Here is how: Software gathers a Web page's content from the computer's operating
system, converts the words and images into a digital version of Braille and then represents that via a touchable row of finger - sized rectangular
cells lined up side by side
like dominoes.
«If ctenophores diverged first, these organ
systems likely have been present in the common ancestor of all animals — and sponges and placozoans must subsequently have lost them — or complex traits
like nerve
cells and muscles must have emerged independently several times in different lineages,» Wörheide explains.
The researchers found that production of this mucus lining depends upon a single immune
system regulator — the NLRP6 inflammasome — that controls mucus secretion by
cells in the wall of the intestine, just
like turning on a faucet.
The
system works just
like a standard glucose meter: patients test their blood using a traditional lancet, then use a special strip stored in the
cell phone to analyze it.
If we can boost the immune
system and allow microglia to do their job and control brain tumor stem
cells, it would be
like removing the seed from the soil — stopping the tumor growth before it starts to get out of control.»
Finally, the team grew the tissue in a three - dimensional
system, which coaxed it into forming all the structures found in gut tissue, including the finger -
like villi that protrude inwards to increase surface area, and recesses called crypts containing the intestinal stem
cells that renew the gut lining weekly (Nature, DOI: 10.1038 / nature09691).
But researchers dream of being able to create truly elastic electronic components — soft circuit
systems that can act more
like live
cells, moving around autonomously and communicating with each other to form new circuits rather than being stuck in one configuration.
«However, cholesterol is involved with many key processes and structures in the body
like cell membranes, bone health and the immune
system.»
What's more, the studies suggest how our gut microbes make the immune
system turn against nerve
cells — a finding that could lead to treatments,
like drugs based on microbial byproducts, that might improve the course of the disease.
The researchers reported the natural inflammatory response when a foreign substance
like a hydrogel is introduced into a
system and draws
cells that secrete proteins involved in cellular infiltration, scaffold degradation, vascularization and innervation.
As of April, telecoms giant AT&T had 3000
systems deployed around the US, boosting mobile broadband coverage in areas
like stadiums and shopping malls where big, expensive
cell masts can not always cope.
«Drugs
like morphine hijack the body's natural painkilling mechanisms, such as those used by endorphins, but because they act within the central nervous
system, they can affect other brain
cells that use similar pathways, leading to side effects such as addiction or sleepiness,» says Professor Gamper.
Although some cancers — particularly those that are rife with mutations
like lung cancer or melanoma — create more tangible targets on the surface of
cells for the immune
system to recognize and attack, other malignancies such as prostate and pancreatic cancers have proved more intransigent.
This growth suggests that the rickshaw could also play a similar emissions - cutting role elsewhere with better engine and communications technologies
like Global Positioning
System and
cell - phones.
Their investigations found that within the endocarp layer — which consists mainly of highly lignified stone
cells - the vessels that make up the vascular
system have a distinct, ladder -
like design, which is thought to help withstand bending forces.
When they find an intruder, the dendritic
cells brandish a sample (think of a most - wanted poster) and rush to the lymphatic
system, where they present it to T
cells, whose role is to form a posse and fan out through the body to hunt down and kill any proteins that look
like the poster.
Then the stem
cells release the interleukin, which is
like a beacon to tell the immune
system to come in and attack, right here.
To T
cells, AdV is
like an alarm ringing at the firehouse, dispatching the fire trucks of the immune
system.
The drug's mechanism of action was entirely new: Instead of attacking cancer
cells (
like chemo), or indiscriminately revving up the immune
system (
like IL - 2), ipilimumab blocked a single receptor on one type of immune
cell.
Because CTLA - 4 acts
like a brake on the immune
system, it prevents the body's defenses from attacking cancer
cells.
«It might sound counterintuitive, but we suggest that this small group of
cells actually functions
like a braking
system for pain,» says Sun.
Neurons are specialized
cells of the nervous
system that communicate using electrical signals, which propagate down long, wire -
like projections called axons.
Thermal fluids are used to alleviate wear on components and tools and for machining operations
like stamping and drilling, medical therapy and diagnosis, biopharmaceuticals, air conditioning, fuel
cells, power transmission
systems, solar
cells, micro - and nanoelectronic mechanical
systems and cooling
systems for everything from engines to nuclear reactors.
There are experiments in using stock market —
like systems, in which people bet on ideas to answer seemingly unanswerable questions,
like when terrorist events will occur or when stem
cell therapy will allow a person to grow new teeth.
The researchers theorize that the segmentation clock works
like other excitable biological
systems that require certain thresholds to be met before sparking an action, such as neurons firing and calcium waves traveling across heart
cells.
Ultimately, we would
like to collect the developmental history of every
cell in the nervous
system and link that information to the
cell's final function.
Researchers have developed the first real - time
system to watch directly through the microscope as Ebola -
like virus particles fuse with human
cells to infect them.
Because human T
cells don't have as many of these brakes, our
cells are a hundred times more aggressive than those of chimps when faced with drugs
like TGN1412, which work by triggering the immune
system.
The Hippo signaling pathway, which is highly conserved up to humans, was known to play a critical role in organ size determination,
like, for example, in the liver, but has not been demonstrated to influence neural stem
cells in the central nervous
system.
A potential solution to this problem is to reprogram other
cell types into functional beta -
like cells, which can produce insulin but are distinct from beta
cells and therefore are not recognized or attacked by the immune
system.
Of course, it makes sense that viruses would choose to turn off genes that the immune
system needs to fight the virus, «
like interferon - b, which is a highly anti-viral gene expressed in virtually all
cell types; or genes that T
cells need to recognize virus - infected
cells,» Kuss - Duerkop says.
As explained by lead researcher, Dr Ferdinand von Meyenn, postdoctoral researcher in the Epigenetics research programme at the Babraham Institute and first author on the paper: «Our method establishes a reliable
system that can be used to explore the early stages of epigenetic reprogramming in primordial germ
cell -
like cells and how this is regulated in the generation of reproductive
cells.
Axons, the long projections of neural
cells which form the nerves of our peripheral nervous
system, are
like electrical cables: they have thick electrical insulation so that they can quickly relay stimuli from the body and signals from the brain to a toe, for example.
In healthy people, brain
cells link together at a single frequency of electrical activity,
like tuning in to a radio station, says Robert McCarley of the VA Boston Healthcare
System and Harvard University.
Though his approach is distinctly different from a donor stem
cell transplant
like Timothy Brown's — in which the entire immune
system is replaced — it is a promising start, with potentially significant clinical benefit and far less risk.
There are these greenfield areas
like the human brain,
systems biology, understanding how
cells work internally, and how the proteins interact inside the
cell.
These intriguing
cells, which are also present in humans, work much
like the Global Positioning
System, allowing animals to understand their location.
Defender
cells would be fiercely fighting off even harmless foreign substances
like the parts of certain kinds of food, for example, as the immune
system would simply not be «tolerant» towards these harmless substances.
Sure, you can get traffic updates radioed to your nav
system or sent to your
cell phone, courtesy of traffic - data providers
like Navteq, based in Chicago, and Clear Channel Radio of San Antonio.