The HCV hypothesis ties in nicely with the Amin A. Nanji research into fibrosis /
cirrhosis and PUFA Vs. SFA, as well as some recent US clinical work on high - carb diets causing fatty liver, and high - fat diets clearing it (linked at The Daily Lipid recently I think) Generating this hypothesis has been
like dropping a pebble in a pond, where every ripple has uncovered a confirmation so far.
Because we've been doing this awhile here at TermLife2Go, we know that a lot of times when you suffer from a condition
like billiary
cirrhosis, you're not really able to work and may not have a ton of discretionary income, especially if you're currently receiving SSI disability.
These toxic stress - induced changes in brain structure and function mediate, at least in part, the well - described relationship between adversity and altered life - course trajectories (see Fig 1).4, 6 A hyper - responsive or chronically activated stress response contributes to the inflammation and changes in immune function that are seen in those chronic, noncommunicable diseases often associated with childhood adversity,
like chronic obstructive pulmonary disease (COPD),
cirrhosis, type II diabetes, depression, and cardiovascular disease.4, 6 Impairments in critical SE, language, and cognitive skills contribute to the fractured social networks often associated with childhood adversity,
like school failure, poverty, divorce, homelessness, violence, and limited access to healthcare.4, 19,58 — 60 Finally, behavioral allostasis, or the adoption of potentially maladaptive behaviors to deal or cope with chronic stress, begins to explain the association between childhood adversity and unhealthy lifestyles,
like alcohol, tobacco, and substance abuse, promiscuity, gambling, and obesity.4, 6,61 Taken together, these 3 general classes of altered developmental outcomes (unhealthy lifestyles, fractured social networks, and changes in immune function) contribute to the development of noncommunicable diseases and encompass many of the morbidities associated epidemiologically with childhood adversity.4, 6