And drug delivery, much
like drug design, is an immensely complex task.
Not exact matches
Sysco says he suspected the technology would need to gain FDA approval from the time the company launched in 2005, because it was
designing an app that physicians would prescribe
like a
drug or device.
I and others of
like mind criticized the
drug culture and related antics as a self - indulgent distraction from the goals of racial justice and peace, and worried that the new enthusiasm for «ecological consciousness» was in fact a conservative ploy
designed to turn the movement away from the cause of the poor.
In a 1992 article in The North American Review entitled «The Corruption of Nobility: The Rise & Fall of Thoroughbred Racing in America,» Ferraro penned a stinging rebuke against
drug abuse on the backstretch, saying, «In general, treatments
designed to repair a horse's injuries and to alleviate its suffering are now often used to get the animal out onto the track to compete — to force the animal,
like some punch - drunk fighter, to make just one more round.
Little Remedies offers a variety of
drug - free products
designed for baby's nose
like Little Remedies ® Sterile Saline Nasal Mist and Little Remedies ® Saline Spray / Drops.
The Food and
Drug Administration is considering tougher oversight of infant formula labeling and advertising to ensure that the often misleading «structure / function» claims companies make («comfort proteins»; «
designed to be more
like breast milk») are valid.
«In contrast to past electrode
designs, this fixed geometry allows accurate measurements that are fully comparable within and between experiments, and that tell us exactly how tissues
like that of lung or gut mature within a channel, keep in shape and break down under the influence of
drugs or other manipulations.»
Next, researchers would
like to study how the two -
drug approach works in humans, although no clinical trials have yet been
designed or scheduled.
But there's a dark side to cancer - killing
drugs designed to match distinct cancer mutations
like a key into a lock.
Grzybowski notes that cancers are more acidic than the rest of the body, so —
like the maze droplets — one could potentially
design drug vehicles to follow the acid - base gradient toward the cancer cells.
Potassium channels are important in irregular heartbeats and diseases such as adult onset diabetes, he notes, and understanding exactly what they look
like improves the ability to
design drugs for treatment.
Ideally, this helps researchers
design drug compounds that perform similar functions but retain attributes needed for successful medicines,
like nontoxicity and the ability to travel through the human body.
In contrast, when rats received a
drug designed to increase the activity of ASIC1a channels in the BLA, the animals displayed less anxiety -
like behavior.
This
drug, which they
designed, works something
like a chemical key that unlocks mitofusin2 and boosts mitochondrial fusion.
Drugs like R121919 were originally
designed to treat generalized anxiety disorder, irritable bowel syndrome and other diseases, but failed to be effective in treating those disorders.
In recent research published in the Journal of Biological Chemistry, Saint Louis University investigators report catching integrase, the part of retroviruses
like HIV that is responsible for insertion of the viral DNA into human cell DNA, in the presence of a
drug designed to thwart it.
Professor Alvaro Mata, from Queen Mary's School of Engineering and Materials Science, said: «The technique opens the possibility to
design and create biological scenarios
like complex and specific cell environments, which can be used in different fields such as tissue engineering by creating constructs that resemble tissues or in vitro models that can be used to test
drugs in a more efficient manner.»
Anderson and Valerie Grum - Tokars, a junior structural biologist on the team, developed a three - dimensional structure of human p38 MAPK, enabling the chemists to
design and synthesize novel
drug -
like small molecules that would disable it.
«Studies
like this also give us a better understanding of how cancer changes to evade treatments — knowledge we can use when we are
designing the new cancer
drugs of the future.»
This unusual binding mechanism opens a new avenue for
drug design: Scientists can consider less rigid protein targets and identify molecules that stabilize more mobile forms of the protein upon binding — somewhat
like a ski boot with an adaptable inner liner that continually adjusts to the foot.
The Wyss team has unveiled not only a novel
design of their «targeted EPO,» but also «targeted interferon alfa,» a cancer
drug that can otherwise cause side effects including flu -
like symptoms, mood fluctuations, and depression.
Like the combination therapies used to treat HIV, scientists could
design a suite of slightly different proteins that targets the hemagglutinin stem region, making it more difficult for the virus to dodge the
drug with a single mutation.
Androgens,
like testosterone, encourage the growth of prostate cancer cells, so scientists
designed drugs called selective androgen receptor antagonists / modulators (SARMs) to block androgen receptors.
Like generic
drugs, so - called biosimilars are
designed to be interchangeable with the biologic they seek to replace.
A new kind of medicine to fight breast cancer is emerging: a
drug combination
designed to act
like a smart...
«The ability to picture what the lock looks
like could help scientists
design more precise
drugs that act on the tau protein and stop damage to the brain.
Led by Prof Sarah Tabrizi of University College London, the TRACK - HD study was
designed to run
like a mock
drug trial.
For several years LPS has been in close cooperation of
drug design with a number of major players in the Polish BioTechMed industry
like Adamed and OncoArendi Therapeutics.
Many activities we do on our phones, from scanning Instagram to playing the game du jour, are brilliantly
designed to behave
like drugs in our brain, hitting our reward systems and making us want to keep going and going and going.
If you're struggling with any of the common psoriasis symptoms such as cracked skin, itchy skin, bleeding or weeping skin, embarrassment, anxiety,
drug side effects, digestive issues, hair, skin, and nail problems, sleeping problems, poor quality of life, etc. — then the Psoriasis Program is DEFINITELY
designed for somebody just
like you!
Rather than wait and see for two long years only to resort later to
drugs designed for breast cancer
like tamoxifen and raloxifene or surgical reduction does not seem
like a health promoting plan of action particularly for a young boy possibly already struggling with self esteem issues.
Oh, and there's a crazy
drug baron supplying the entire world with narcotics who lives in a jungle compound
designed to look
like an American diner.
Fishman creates sculptural paintings — large, constructed installations with hypersaturated colors and industrial -
like slick surfaces — that evoke the
design of pills, their combinations in
drug «cocktails,» and the colors and surfaces of
drug advertising.
It is legal to
drug test your employees, and prospective hires, but
like any background screening program, it must be carefully
designed to comply with regulations.