Not exact matches
Stem cells from breast milk can grow into many other kinds of human
tissue, raising hopes of an ethical source of
embryonic -
like stem cells
The newly discovered human cells, named «cord - blood - derived
embryonic -
like stem cells» or CBEs, are not quite as primitive as
embryonic stem cells, which can give rise to any
tissue type of the body.
If you put
embryonic stem cells on a substrate
like Jell - O — mechanically similar to brain
tissue — they turn into neurons.
Like a Texan who keeps his drawl after moving to California, adult cells reprogrammed to resemble
embryonic cells retain some signatures of the
tissue from which they came.
Organlike
tissue bits can be generated from pluripotent stem cells that are either plucked from embryos or created by taking a person's adult skin or blood cells and chemically inducing them to revert to an
embryonic -
like state.
And so they have long sought haploid
embryonic stem cells, which can become any kind of
tissue but contain just one set of genes,
like a sperm or egg.
A group that included researchers at the Wellcome Trust Sanger Institute and the University of Cambridge, both in the United Kingdom, developed a possible treatment for A1ATD by first reprogramming a skin cell from a patient into iPS cells, which are
embryonic -
like cells that can develop into many
tissue types.
Reprogramming adult cells to function
like embryonic stem cells is one way researchers hope to create patient - specific cell lines to regenerate
tissue or to study specific diseases in the laboratory.
The new cells, which Yamanaka called induced pluripotent stem (iPS) cells, looked and behaved
like embryonic stem cells, which are prized for their ability to transform themselves into almost any kind of
tissue and, perhaps, someday cure disease — a more distinct possibility now that President Barack Obama has loosened restrictions on stem cell research.
Tumors were suspected to be
tissues that had been triggered to become
embryonic -
like again, and it is now generally accepted that tumors are indeed more «
embryonic» than the
tissues they are derived from, due to the re-expression of
embryonic - related genes.
This finding complements previous research from the University of Edinburgh and the National Institute for Medical Research which showed that
embryonic stem cells can be coaxed into this spinal cord cells; however, the Cambridge researchers showed that the in the embryo -
like aggregates, the structural organization is more robust and allows for the polarised growth of the
tissue.
iPSCs are cells that can be take from adult
tissue and «reprogrammed» into
embryonic stem cell (ESC)-
like cells.
Nearly 150 years ago, Julius Cohnheim first proposed the CSC hypothesis (also called the «embryonal - rest theory») that suggested the presence of
embryonic -
like cancerous cell remnants in adult
tissues that can develop into cancer in a non-spontaneous way (1).
2007 also saw one of the most game - changing developments in the stem cell field; researchers learned how to create cells
like embryonic stem cells, but instead of coming from an embryo these cells are created from adult cells, potentially cells from any
tissue in the human body.
The idea of reprogramming a cell from adult
tissue into an
embryonic -
like cell existed long before the creation of iPS cells.
The relationship between cancer and
embryonic tissues was first proposed in the 1870s by Francesco Durante and Julius Cohnheim, who thought that cancers originated from cells in adults that persist in an immature,
embryonic -
like state.
This approach to derive patient - specific
Embryonic Stem cell -
like cells (iPS cells) is going to open up research into the genetic causes of disease and the search for therapies not only for such diseases, but also for repairing
tissues damaged in other ways.
The idea of reprogramming a cell from adult
tissue into an
embryonic -
like, pluripotent cell existed long before the creation of iPSCs.
The Ubx - abdA genes —
like other homeotic genes, including the one that can cause a fruit fly to grow a leg out of its head — orient the
embryonic tissues as to where they lie in the body.
Some researchers are using induced pluripotent stem (iPS) cells —
tissue - specific cells (usually skin cells, but sometimes other
tissue cells) that are reprogrammed in the lab to behave
like embryonic stem cells — to grow rods and cones or RPE cells.
Some scientists cite this potential in saying the true moral course is to accelerate research on
embryonic cells because it might produce transplant
tissue for illnesses
like diabetes and Parkinson's disease.
Neural stem cells are found in adult or fetal brain and spinal cord or derived from
embryonic stem cells, which have the capacity to become any cell type in the body, or induced pluripotent stem (iPS) cells,
tissue - specific cells that are reprogrammed in the lab to behave
like embryonic stem cells.