Sentences with phrase «like exome sequencing»

Ironically, another reason people like exome sequencing is because of the limited scope: it essentially doesn't interrogate the regions (noncoding) and variant types (SVs) that are more difficult to interpret.

Not exact matches

Using technologies like whole genome or whole exome (the protein - coding portion of the genome) sequencing requires specialized equipment and advanced data analysis and is still relatively expensive.

And let's face it, exome sequencing lets us conveniently avoid some of the most challenging aspects of human genomics, like detecting complex rearrangements (SVs) and interpreting noncoding regulatory variants.

Numerous pilot programs, like the NIH's Undiagnosed Disease Network, are using exome sequencing to cases like these.

A cohort like the one in the AMD study (44,000 samples) probably costs $ 2.2 million to genotype, compared to sequencing costs of $ 9.7 million (exome) to $ 45 million (whole genome).