Sentences with phrase «like ipilimumab»

Checkpoint inhibitors like ipilimumab — which has been on the market since 2011 — nivolumab, and pembrolizumab stop tumor cells from stimulating the receptors.

In December 2014 the FDA approved Opdivo (nivolumab), which, like ipilimumab, is another checkpoint inhibitor to treat melanoma.

Not exact matches

The drug's mechanism of action was entirely new: Instead of attacking cancer cells (like chemo), or indiscriminately revving up the immune system (like IL - 2), ipilimumab blocked a single receptor on one type of immune cell.

Hodi designed this investigator - initiated clinical trial to find out if giving sargramostim along with ipilimumab would have a synergistic effect against the melanoma — like pressing the immune system's accelerator while releasing the brake.