If the hostel your staying at comes with lockers, make sure you bring your own combination lock (I don't
like key locks because then it's another thing to worry about).
Not exact matches
A bit
like a PIN, the private
key can be stored offline in a text file or even on a piece of paper
locked in a safe, where hackers can't get to it.
The details are complex, but the basic idea, oversimplifying quite a bit, is that Apple's backup systems will act a
like a giant iPhone: User data is protected with a combination of the user's password and a strong encryption
key that's physically
locked into a hardware module and can't be easily extracted.
They remind us about what truly matters and sometimes, they make our misadventures (
like locking your
keys in the car, forgetting to pick up gifts altogether, or lost luggage) seem totally normal.
It is
like a precious
key to a
locked door that we can not find.
Pies and chocolate go together
like a
lock and a
key.
Like lock me up and throw away the
key kind of love.
When he
locked up Steph from the top of the
key to the rim, and swatted his weak stuff literally into his face, and then acted
like it was just another day at the office, was another «this kid is gonna be legit» moments.
The first lesson I learned is to not stick your car
keys and phone in that bag, if the babies fall asleep and the car is
like mine and automatically
locks, you are now arms full of sleeping babies to get to the
keys.
«Sometimes, getting the baby into the pelvis is
like fitting a
key into a
lock,» Hartley says.
Dr Ranjit Gill, chief clinical officer of Stockport Clinical Commissioning Group, told the Manchester Evening news, «this fits our plans
like a
key in a
lock... the deal will be really good for patients in Greater Manchester and will help us join up NHS care with social care for the first time».
The researchers were on the lookout for molecules that could bind precisely with defective RNAs —
like keys fitting in the right
locks.
Using an artificial version of the protein Izumo, found on the surface of sperm, the team scoured the genetic sequences of millions of proteins until they found one that attached itself to Izumo,
like a
key in a
lock.
Like a
key fitting into a
lock, the carrier molecules bind to certain receptors or biomarkers and the radioactive atoms enable PET or SPECT scanners to image areas where the tracers have collected in large numbers.
The enzyme pocket has a special shape so that only one specific substrate is able to bind to it, just
like only one
key fits into a specific
lock.
The reigning but still unproved explanation of smell supposes that the shape is the thing, with receptors fitting
like a
lock into the molecule's
key.
Lanza also designed the nanoparticles to carry targeting molecules that home in on and bind to cancer cells that carry the complementary receptor,
like a
lock and
key.
The way molecules and receptors work, it's
like keys fitting into
locks.
«We need to design nanoparticles that will,
like a
lock - and -
key mechanism, travel through the body and interact only with the diseased cell surface,» says Marth.
In the hippocampus and the amygdala, areas of the brain thought to be associated with episodic memory, researchers had shown that the chemical signaling agent called glutamate acts
like a
key in the
lock of some of these protein «flood gates.»
But there's a dark side to cancer - killing drugs designed to match distinct cancer mutations
like a
key into a
lock.
«It's almost
like a
lock and
key.»
Folded proteins tend to bind to their targets firmly,
like a
key in a
lock, at just one or two spots, but their more stretched - out wiggly cousins are
like molecular Velcro, attaching lightly at multiple locations and releasing with ease.
Wang's technology uses nanoparticles that are shaped to fit
like a
lock - and -
key to either THC or to reagents attached to a surface.
Knowing its molecular structure could allow for the development of tailor - made drugs that fit to the receptor
like a
key into a
lock.
This small protein molecule contains a loop which fits,
like a
key in a
lock, into the ion channel proteins found on nerve cell membranes, which are used to transport sodium and potassium ions in and out of the cell.
Not every PY motif binds to every WW domain; the interaction is specific,
like a
lock and
key.
Insulin can open up a cell's outer membrane
like a
key in a door
lock and set in motion the machinery that feeds the cell glucose, which is converted to energy.
Then the understanding evolved — it was found that not all protein «
keys» are rigid, some are more
like boiled spaghetti which can still operate the rigid
lock successfully, by adjusting its shape.»
A hormone is
like a microscopic
key floating in the bloodstream: When it finds a matching
lock, it binds to the receptor and triggers the cell to do something, such as grow or divide.
Thornton, for example, has studied the evolution of hormones and their receptors, which fit together
like lock and
key.
«It's
like resistance is a
lock and venom is the
key and I have to have the right
key to open my office and another one to open the office next door,» Holding said.
If any of these structures which fit the T - cells» specific receptors
like a
key fits the right
lock — then the T - cell will proliferate and set off a series of signals, starting the process of eradicating the diseased cell.
These signals generally work
like a
key (the peptide) fitting into a
lock on the surface of a cell (the protein receptor).
Adenosine helps to sustain such cells by fitting into a protein called the A2A adenosine receptor on their surfaces,
like a
key into a
lock.
To cause an infection, viruses work
like a
lock and
key, attaching to specific receptors on cells to take hold and spread.
These cells contain receptors that accept certain bacteria only —
like a
lock waiting for the right
key.
Interestingly, the dominant model for the mechanism by which a small molecule
like a drug fits into the active site of a disease - promoting enzyme and modulates its activity is that of a «
lock and
key».
Gern explains that the genetics of the receptor — which serves
like a
lock - and -
key mechanism that allows the virus to enter and infect a host cell — influences who is likely to be most affected by the virus.
Using computer simulations called molecular docking, team members screened more than 3 million molecules to find some 2,500 that fit the mu receptor
like a perfectly cut
key in a
lock.
«Conventional antibiotics are
like keys in a
lock,» explains Zasloff.
Those hormones fit
like keys into «
locks» on the outside of a cell.
The epitope is located in the antigen where the antigen molecule docks,
like a
key that opens the
lock.
Therefore, each tRNA has a specific three - nucleotide sequence called an anti-codon that matches up with the appropriate mRNA codon,
like a
lock and
key.
Later on, scientists identified a molecule, B7 - H1, subsequently renamed PD - L1, which binds to PD - 1, clicking
like a
key in a
lock.
Top with the cloth eye patch to
lock in both moisture and
key ingredients
like caffeine.
A xenoestrogens will be recognized by the body as an estrogen, and it will attach to the same receptors as estrogen,
like a
key fitting one type of
lock.
A
key tip at this age is to invest in quality hair care,
like the Shu Uemura range, to ensure your
locks are in their best condition.
Synthetic hormones fit more
like a skeleton
key in some, but not all, hormone receptor («
lock») sites.
It acts very much
like a
lock and
key.