Sentences with phrase «like luminal»
I'll be looking to change a color and something comes up on the screen, like a luminal phase between a green and a red.
http://marketingforwriters.com/ Not exact matches
Human breast cancers can be classified according to their histological and molecular features into different subtypes, including luminal, ERBB2 and basal - like tumors.
«It was really surprizing to realize that oncogenic Pik3ca in basal cells induced the formation of luminal tumours, while its expression in luminal cells gave rise to heterogeneous and more aggressive tumors including basal - like tumors,» comments Alexandra Van Keymeulen, the first author of the paper.
«This opens up the possibility that cancer subtype - specific signaling is driven by STAT3 and that STAT3 inhibitors may be more effective in patients diagnosed with basal - like cancers than in those with luminal cancers,» Horvath said.
Horvath and Tell identified 84 genes that are expressed differently in basal - like cancer tumors as compared to luminal cancer tumors.
The results suggest a clinical study should be conducted of a STAT3 - inhibiting drug in patients with basal - like and luminal cancers, Horvath said.
The four types are luminal A, luminal B, HER2 - enriched and basal - like.
The Cancer Genome Atlas study encompasses more than 500 primary tumors representing the four intrinsic subtypes of breast cancer: Luminal A, Luminal B, Her2 - enriched, and Basal - like.
The observed mutation rate in coding regions seems to reflect the aggressiveness of breast cancer subtypes: lower in luminal A (0.84 mutations / Mbp) than luminal B (1.36 mutations / Mbp), higher in Her2 - enriched (2.05 mutations / Mbp) and Basal - like (1.68).
Genetically altering lab mice, they made sure the gene known to cause luminal - like breast cancer was present but they also inactivated the cyclin D1.
The Tufts team discovered that luminal - like breast cancers (the two most common types, and which are sensitive to hormones) originate from self - renewing cells known as lobule progenitors.