Because according to her you can't use something
like telomerase to increase the length of your telomeres without significantly increasing your risk of cancer.
Not exact matches
Pioneers
like Dr Dean Ornish and Dr Caldwell Esselstyn where among the first to show that if you combined a low fat, plant based diet, with walking and stress management, not only could you prevent and reverse heart disease (and many other chronic conditions), but you could also increase
telomerase activity.
For now, the only diseases clearly caused by shortened telomeres or dysfunctional
telomerase are rare premature aging disorders
like dyskeratosis congenita.
«That makes fooling with
telomerase look
like child's play.»
We used liposomes — which are almost
like tiny soap bubbles in the bloodstream — to deliver a gene that knocks the
telomerase RNA down.
While increased
telomerase activity could bring youth to aging cells and cure premature aging -
like diseases, too much of a good thing can be damaging for the individual.
Scientists say that the findings are exciting because, though disrupting
telomerase has looked
like a good strategy for treating cancer, it's been difficult to pinpoint compounds that do so.
Telomerase is turned off in most human cells, but cancer cells often must reactivate it so that they can keep dividing
like crazy.
For example, labeling of these cells with stem -
like cell associated markers (p63, nestin, and
telomerase) have heavily implicated these cells as stem cells [13].
The data presented in this report (
telomerase activity and BrdU - linked alkaline phosphatase activity staining) suggests that cells in the corneal endothelium may be renewed by stem -
like cells located in a niche at the posterior limbus.
Methods: Human corneas with attached scleral rims were obtained from eye banks and were assayed for
telomerase activity and BrdU (bromodeoxyridine) incorporation to determine, respectively, the presence of a stem -
like cell marker and replicative activity.
It is ironic that an AGE breaker
like Carnosine activates
telomerase.
This little - heralded, meticulous investigation into the effects of ablation of the
telomerase catalytic subunit in mice with human -
like telomeres provides us with strong reassurance that, should it prove to be the preferred approach for implementing the OncoSENS strategy, the effects of knocking out TERT would be limited to those dictated by the loss of telomere - lengthening per se, and would not lead to an unintentional loss of some essential but hitherto - unknown phsyiological function.