These findings reinforce many things that we already know: that mutations acquire gradually with age, that most of the mutations in AML (and
likely other tumors) are random background events not contributing to tumorigenesis, and that subsequent mutation and evolution can give rise to subclones that ultimately determine cancer progression and response to therapy.
Not exact matches
Triple - negative
tumors are aggressive and more
likely to metastasize than
other breast cancers, and there is no effective treatment.
Cells suspended in a stiff matrix were more
likely to work their way through the matrix to
other side of a serum gradient, analogous to how metastasizing cancer cells break free from their
tumors.
Triple - negative
tumors are also more
likely to spread and recur than
other types of breast cancers.
Instead, researchers told the European Breast Cancer Conference that their findings suggest that extending screening programs to older women results in a large proportion of women being over-treated, and at risk from the harmful effects of such treatment, because these women were more
likely to die from
other causes than from any
tumors detected in the early stages of growth.
«This study supports the idea that we could test ovarian cancer
tumors and say they're more
likely to respond to one or the
other drugs,» Diamond says.
Philip Laipis of the University of Florida, who has also observed
tumors in AAV vector - treated mice, agrees, at least for studies using a similarly high dose of AAV to target liver cells, which are more
likely than
other cell types to take up the AAV vector.
If
tumor cells are not present in the sentinel node, the primary
tumor most
likely has not spread to lymph nodes or
other organs.
Researchers at Washington University School of Medicine in St. Louis have discovered why breast cancer patients with dense breasts are more
likely than
others to develop aggressive
tumors that spread.
For example, HPV - inactive
tumors were 17 times more
likely to contain TP53 gene mutations — which are common in
other cancer types — than HPV - active cervical cancers.
Tumors with high levels of E-cadherin tend to be tightly tethered to nearby cells and less
likely to break free and travel to
other sites.
So if we assay a panel of
tumors and see that half the
tumors have a mutation in gene A, and the
other half have a mutation in gene B, with no overlap, it's quite
likely that the mutations play similar functional roles.
These two histones thus have a key role of epigenetic silencing of
tumor suppressor genes in breast cancer (and
likely other cancers), suggesting that they may represent new therapeutic targets.
Melanoma is more
likely than
other skin cancers to spread beyond the initial
tumor site to
other organs, but all the patients had localized disease.
Dogs that are affected with internal HSA often have an irregular heartbeat, and are
likely to have intermittent episodes when their
tumor will bleed, causing their gums and
other mucous membranes to turn pale.
If a parent has bone or joint disease, allergic skin disease, bad teeth and gums, ear infections, eye problems, separation anxiety, destructive behavior, tender feet (cutting toe nails), oily musty skin odor, coprophagy, liver, heart or kidney disease, bladder stones, asthma, fatty
tumors, poor physique or coordination, umbilical and
other hernias or another disease, then the puppy is at least ten times as
likely to inherit these problems than a puppy from healthier parents.
For example, a grade 1
tumor is the least
likely to spread to
other organs, with a better survival rate.
From experience, veterinarians know that some
tumors are more
likely to spread than
others.
As is true for
other tumors, early detection is
likely to offer the highest probability of successful treatment outcomes.
Since we are
likely to get another Golden (although no
other dog will replace our beloved, Teddy) I was wondering if you could answer these questions for my future reference: 1) Was it possible that she had something
other than a brain
tumor given the negative blood work and x-rays and, if so, were there
other diagnostic studies
other than an MRI that we should have looked into?
If she suspects bladder stones,
tumors or
other abnormalities, she'll
likely want X-rays or ultrasound images of your dog's abdomen.
Tissue reaction / allergy / foreign body: he could have a splinter or something that got walled off Insect bite that caused a granuloma Lipoma: if it is movable and small and soft (but not necessarily 100 %) it could be a fatty benign
tumor Other neoplasia (I could go on and on but Dexter younger, so it is less
likely) MCT Etc. ect... the tests need to be done to determine the cause
Grade III (high - grade)
tumors are the most invasive and aggressive and the most
likely to spread to
other parts of the body.