Not exact matches
Or stem cells injected into a patient as therapy might be designed so that their
tumor suppressor genes are less
likely to mutate and cause cancer.
These two histones thus have a key role of epigenetic silencing of
tumor suppressor genes in breast cancer (and
likely other cancers), suggesting that they may represent new therapeutic targets.
When mutated, or not working properly, cells with abnormal
tumor suppressor genes are more
likely to grow out of control and lead to the development of cancer.