Two key
limitations of previous studies, however, make it difficult to draw firm conclusions from their results — limitations that we address in this study.
To address
limitations of previous studies, the review included 11 clinically and geographically diverse cohorts.
The methods used in the new peer - reviewed paper specifically address
the limitations of the previous study.
Not exact matches
Jeffrey Kidd, Ph.D., an Assistant Professor
of Human Genetics and Computational Medicine & Bioinformatics who worked on the new
study, notes that only recently has it become possible to sequence Y chromosomes, because
of technical
limitations of previous approaches.
However, due to technological
limitations,
previous genetic
studies largely focused on mixed populations
of cells, obscuring critical nuances in cellular behavior.
Previous studies have not examined how working or volunteering affects functional
limitations, said Ben Lennox Kail, lead author and assistant professor in the Department
of Sociology at Georgia State.
A potential
limitation of the
study is the higher dropout rate for patients randomly assigned to surgery, as reported with
previous TAVR trials.
The
previous studies had some key
limitations, including a lack
of data on other risk factors.
«Despite the
limitations of a single arm, non-randomized
study, we infer from these data that Interferon ß - 1a treatment is worth further consideration for the treatment
of Ebola virus disease,» said Dr. Fish, who is also a Professor in the Department
of Immunology at the University
of Toronto, noting that the decision to undertake the clinical trial was based on
previous preliminary scientific data, and on the fact that no currently approved antivirals exist to treat Ebola.
A
limitation of both
of the
previous studies was the absence
of other macronutrients (aside from protein in whey) consumed during the 12 - hour postexercise period.
Another
limitation of the
study is that EC use in the clinic access group was relatively high compared with
previous studies.4, 6 High use rates in the control group may explain why we did not observe a difference compared with the pharmacy access group.
One
limitation of the present
study is the unfavourable internal consistency
of the 20 - item MHKQ scale (Cronbach's α = 0.61), which is in keeping with
previous studies showing weak to acceptable internal consistency.10, 11, 29 However, this may be due to the fact that for knowledge scales measuring various factors
of a construct, knowing the correct answer
of one item does not necessarily lead to the right recognition
of another item, thus a very high internal consistency may not be expected.
In conclusion, despite its
limitations, this
study supports and extends the findings
of previous reports showing that the MAOA polymorphism in combination with early experience modulates individual proclivity to later - life physical aggression.