Sentences with phrase «lineage analysis studies»
Our group is contributing to this knowledge by using transgenic mice to perform loss - of - function, gain - of - function and lineage analysis studies.
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Those studies were based on an analysis restricted to mitochondrial DNA, which is passed along via the maternal lineage.
Thus, this study has implications for analysis of human vaccine studies, as in addition to searching for defined lineages it is worthwhile to perform functional analysis of monoclonal antibodies that may have found new structural solutions to high affinity binding which can not be discerned from DNA sequence alone.
The most recent study regarding the analysis of Ötzi's complete mitochondrial DNA, conducted in 2008 by other research teams showed that the Iceman's maternal lineage — named K1f — was no longer traceable in modern populations.
Analysis of pseudogenes showed lineage specific loss of some functions, notably with several Pmp and TMH / Inc proteins predicted to be inactivated in many of the isolates studied.
A broad scale analysis of the evolutionary relationships of Urocyon lineages should be conducted because in this study, we found that eastern and western gray fox populations are more deeply diverged than the two currently recognized species of California Urocyon (S2 Fig.).