Nearly all of the affected children had the HLA - QB * 06:02 gene variant already
linked with narcolepsy.
Not exact matches
In recent sleep lab studies of 600 people age 30 or older, Mignot was surprised to find that 1 percent — or 20 times as many as
with classic
narcolepsy — suffered from inordinate sleepiness, had a high frequency of the autoimmune marker
linked to
narcolepsy, and went very rapidly into REM when they napped.
Through his work
with large patient groups, he has managed to show that
narcolepsy is closely genetically
linked to so - called HLA molecules, which play a key part in the immune system by presenting foreign substances to immune cells.
While it's most common in people
with narcolepsy, it's also
linked to lack of sleep and an irregular sleep schedule, says Dr. Walia.