Sentences with phrase «lipid accumulation»

Perhaps, for example, we can find a way to block the toxic lipid accumulation.

In fact, studies have shown that omega 3 fatty acids reduce lipid accumulation and liver enzyme levels, improve insulin sensitivity, and have anti-inflammatory effects (7).

BPA exposure of cell suspensions results in lipid accumulation in adipocytes and hepatoma cell lines [49].

«We realized that Dr. Alois Alzheimer himself had noted the presence of lipid accumulations in patients» brains after their death when he first described the disease in 1906.

The study represents the first time researchers were able to visualize the distribution and dynamics of fatty acids in such detail inside living cells, Shen added, and it revealed a previously unknown toxic physical state of the saturated lipid accumulation inside cellular membranes.

«We have shown that an endogenous peptide, catestatin, can directly suppress glucose production from hepatocytes and can indirectly suppress lipid accumulation in liver as well as macrophage - mediated inflammation in obese mice,» said Sushil K. Mahata, PhD, professor of medicine at UC San Diego School of Medicine.

Why It Matters: This study sets the stage for efforts to engineer yeast to optimize lipid accumulation and maximize the yield of carbon - based products.

To address this gap in knowledge, Pacific Northwest National Laboratory researchers performed the first comprehensive metabolomics and lipidomics study on Y. lipolytica to characterize metabolic processes associated with lipid accumulation in the yeast species.

They identified and characterized major pathways involved in lipid accumulation from glucose in Y. lipolytica.

Moreover, the new comprehensive dataset describing lipid accumulation in Y. lipolytica will enable more detailed experiments to provide specific genetic targets for future metabolic engineering efforts.

However, the highest proportion of a biofuel - friendly lipid occurred at 24 hours, suggesting the biofuel quality of the lipids was highest prior to peak lipid accumulation.

She pursued her studies in Pierre et Marie Curie University (Paris 6), France, where she obtained her MSc in Biochemistry - Pharmacology in 2008 and her PhD degree in Physiology & Physiopathology in 2011, focusing on the role of the Wnt / β - catenin signaling on intramyocellular lipid accumulation during obesity and type 2 diabetes.

Impaired lipid metabolism with excess release of FA from adipose tissue leads to overspill of circulating lipids and thus to ectopic nonadipose lipid accumulation in the liver hepatocellular lipids (HCL), muscle intramyocellular lipids (IMCL), and myocard myocardial lipids (MYCL) with detrimental consequences of lipotoxicity.

Gender difference in hepatic steatosis index and lipid accumulation product ability to predict incident metabolic syndrome in the historical cohort of the Brisighella Heart study

Technically, this is called intramyocyte lipid accumulation.

Antibiotics protect against fructose - induced hepatic lipid accumulation in mice: role of endotoxin.

It assists in the breakdown of fats and the prevention of excess lipid accumulation in the liver and arteries, which could obstruct blood flow to the brain, heart, and kidneys.

Ignorance has prevailed over the interrelationship between muscular lipid accumulation, chronic inflammation and insulin resistance because the central mediating factor is magnesium.

Based on these observations, sex - specific body shape and lipid accumulation could already be determined in utero, especially in insulin sensitive locations varying by fetal sex.

Red Yeast Rice is a supplement that inhibits fat cells (adipocytes) by interfering with cellular activity and lipid accumulation may be useful for pets with fatty tumors.

Comment: Lipid accumulation can be seen with pancreatitis, endocrinopathy, hepatocellular insult, neoplasia, idiopathic, and other rare conditions.

Hepatomegaly due to lipid accumulation is common in diabetic dogs and cats.