Compared with levels in a control group,
certain lipid metabolites were elevated in the transgenic mice, even though they appeared perfectly healthy.
The report, published online in the Proceedings of the National Academy of Sciences, suggests that it may be possible to prevent the vision loss observed in wet AMD by increasing the expression of specific bioactive
lipid metabolites in the retina.
The study also identified several
new lipid metabolites whose high concentrations were associated with improved insulin resistance and reduced risk of diabetes.
Sex had a small but significant impact on the genetic T2DM risk model, which disappeared in the combined genetic and
lipid metabolites risk model in the Framingham offspring cohort (196).
The greatest differences in the metabolic profiles of those who developed type 2 diabetes and those who didn't were observed in the concentrations of indolepropionic acid and
certain lipid metabolites.
Research has shown that calorie restriction changes the levels of hormones and
lipid metabolites, and alters energy metabolism.
Similarly to indolepropionic acid, high concentrations of
these lipid metabolites also seemed to protect against low - grade inflammation.
Vitamin C as Pureway - C ®, a Sustained Release Vitamin C contains Vitamin C -
lipid metabolites, citrus bioflavonoids, and ascorbyl Palmitate for maximized absorption and retention.