Since normal kidneys allow very
little albumin protein in your pet's blood to escape into its urine, there are tests that check for its increased presence without comparing it to the amount of creatinine that is present.
In Ames dwarrf, Snell Dwarf mice, Klotho mice, GHKO mice who have
little IGF and GH; and live longer than wild - type; we see that indeed insulin and glucose / nutrient / energy pathways (which create oxidative stress through excessive nutrient via elevated glycation blood glucose creating high glycated
albumin and hemoglobin), that aging is acted on by IGF through hormones, GFs, GHs, acting on insulin signals, which act on survival genes (DAF / SIRT / FOXO).