Sentences with phrase «live cell and tissue»

With the high sensitivity and speed required for live cell and tissue imaging and the ease of use and flexibility required for microplate imaging and complex screening protocols, FV3000 brings complete workflows from live cell 2D - 4D imaging through image processing such as deconvolution, and analysis.

Campbell has developed a new technique, which he has dubbed FPX, that employs genetically encoded fluorescent proteins to image dynamic biochemical events in live cells and tissues.

The high MAO - B activity consistently observed in patients with Parkinson's disease has been proposed as a biomarker, but there has been a lack of suitable small molecule probes for MAO - B specific detection in live cells and tissues.

Microscopes make living cells and tissues appear bigger.

Our most recent work potentially opens the integration of voltage - sensitive nanomaterials into live cells and tissues in a variety of configurations to achieve real - time imaging capabilities not currently possible.»

Researchers at Columbia University have made a significant step toward breaking the so - called «color barrier» of light microscopy for biological systems, allowing for much more comprehensive, system - wide labeling and imaging of a greater number of biomolecules in living cells and tissues than is currently attainable.

Not exact matches

He earned degrees in cell biology and tissue engineering and eventually got a job in a lab run by Vladimir Mironov, who was investigating the use of bioprinting — 3 - D printing using living cells — to generate replacement organs.

Pro-choice euphemisms like «pre-embryo,» «foetal tissue,» and «ball of cells» are materialistic and reflect fully the diminishment of human life as chance — easy come, easy go.

Such was the comfortable vista which, less than a century ago, began abruptly to change beneath our gaze, something in the fashion of those organic tissues in the living body which, after long remaining harmless and dormant, their cells apparently indistinguishable from those of the surrounding tissue, suddenly burst into dangerous growth.

If we could but restore or bring about the normal functioning of brain cells and nerve tissues, as well as their own subsidiary chemical activity in such cases, then mental life would come flooding back in fullness and richness.

The doctor can set the bone, cut out the tissue, or administer the drug, but only the mysterious life force itself can join cells back together again and restore chemical balance.

This allowed them to track changes in calcium ion concentrations in the cells around wounds in living tissue (as opposed to the cell cultures used in many previous wound response studies) and to do so with an unprecedented, millisecond precision.

Despite a tremendous amount of scientific study, many outstanding mysteries still surround the way in which cells in living tissue respond to and repair physical damage.

The fields within biology are further divided based on the scale at which organisms are studied and the methods used to study them: biochemistry examines the fundamental chemistry of life; molecular biology studies the complex interactions of systems of biological molecules; cellular biology examines the basic building block of all life, the cell; physiology examines the physical and chemical functions of the tissues and organ systems of an organism; and ecology examines how various organisms interrelate.

By plucking out delicate, live tissue during neurosurgery and then studying the resident cells, researchers have revealed a partial cast of neural characters that give rise to our thoughts, dreams and memories.

Scientists are forced either to experiment on whole animals, which is expensive, raises ethical issues and may not predict effects in humans, or to perform tests on microscopic human cells found in tissue cultures, which have been altered to live forever and bear little relation to actual living, breathing people.

Combining living tissues and technology, Jiawei Shao et al. created custom cells that produced insulin when illuminated by far - red light (the same wavelengths emitted by therapy bulbs and infrared saunas).

An analysis of the HPV16 genome from 5,570 human cell and tissue samples revealed that the virus actually consists of thousands of unique genomes, such that infected women living in the same region often have different HPV16 sequences and variable risks to cancer.

The individual live cells are not communicating, and «cells in a tissue have to communicate with each other».

«ENCODE is a living project and the maps that are generated are constantly updated and improved, with information being added on new types of cells and tissues or new complementary genome assays.

Defined as the harnessing of living processes to achieve healing and repair of damaged and diseased tissues by Tim Hardingham, director of the UK Centre for Tissue Engineering, it is a field that requires collaborative research involving cell and molecular biologists, chemical engineers, materials scientists, and surgeons.

«Knowing how cells respond to mechanical cues in the living embryo and how they physically sculpt tissues and organs in the 3D space will transform the way we think about developmental processes,» said Otger Campàs, a professor in the Department of Mechanical Engineering at UCSB and senior author on the paper that reports this novel technique in Nature Methods.

«It has been shown in mice that live immune cells in breast milk pass through the intestinal mucosa into the blood circulation of the pups and engraft in various tissues,» says Hassiotou.

Four weeks after the team switched on the enzyme, they found that tissue had regenerated in several organs, new brain cells were developing and the mice were living longer.

Combining tissue engineering and the same micro-fabrication techniques that are used to produce computer chips, Harvard University cell biologist Don Ingber and his colleagues have built a living, breathing synthetic lung — albeit one just the size of a quarter.

Mark Bates has been named the 2010 Grand Prize winner for the GE & Science Prize for Young Life Scientists for his novel research to obtain high - resolution images of biological cells and tissues.

The enzyme, called tankyrase, may prove useful for extending the lives of cultured cells grown to repair burned skin and other damaged tissue.

Deleting telomere elongation capacity throughout the body would also be life - threatening, because it would mean that our regular proliferating cells (like those in the skin or the lining of the gut) would suddenly have iron limits on their ability to reproduce themselves and thus replenish tissue.

So far the biggest advances have been with thin tissues such as skin, blood vessels, and bladders (Science, 16 April 1999, p. 422 and 19 November 1999, p. 1493), because foams with holes big enough to house living cells tend to come in thin sheets.

Besides displaying more natural signaling patterns, 3D cultures allow researchers to mix cell types in ways that mimic their interactions in living tissue, providing more accurate models of normal physiology and pathogenesis.

In a recent study published in Angewandte Chemie International Edition, Associate Professor of Chemistry Wei Min's team developed a new glucose analogue that can mimic the natural glucose, and imaged its uptake as energy source by living cancer cells, neurons and tissues at the single cell level.

The new work, by James Mitchell at the Harvard School of Public Health and colleagues, suggests that holding back calories causes cells to produce hydrogen sulfide, which somehow makes tissues more resilient and prolongs the life of laboratory organisms.

To overcome these problems, Min and his team developed a new modality to visualize glucose uptake activity inside single cells based on stimulated Raman scattering (SRS) imaging, and demonstrated its use in live cancer cells, tumor xenograft tissues, primary neurons and mouse brain tissues.

In the current study, the researchers took diaphragm tissue from donor rats and removed all the living cells from it using a series of chemical treatments.

The authors said these results suggest that LPE «may improve shelf life by maintaining membrane integrity, reducing respiration, and slowing the breakdown of starch and cell walls during ripening and senescence of banana fruit tissue.»

Historically, clinicians evaluating a patient for transplant have sought to identify donor cells that are perfectly matched to the patient's cell type, which is considered to be the optimal approach to help ensure successful outcomes and to minimize risk of graft - versus - host disease (GVHD), a serious and potentially life - threatening complication that occurs when the donated immune cells attack the patient's cells as foreign tissue.

The team hopes to apply this method to the nerve cells, bone marrow, and brain tissue of living animals and humans.

Using a powerful imaging technique that allowed the scientists to track the presence and movement of parasites in living tissues, the researchers found that Toxoplasma infects the brain's endothelial cells, which line blood vessels, reproduces inside of them, and then moves on to invade the central nervous system.

The use of cell surface markers to isolate specific cell populations is one common method for separating cells; however, isolating live cells based on their RNA expression is a powerful new way enabling the study of small cell niches in nongenetically modified animal models and human tissue.

SUSHI also visualizes synaptic clefts for the first time in slices of live tissue and reveals glia - neuron interactions and cell migration.

The population of T cells that remains are tissue resident memory cells, which live long term in skin and, when functioning properly, should be fighting infection.

In contrast to necrosis, which is a form of cell death that results from acute tissue injury and provokes an inflammatory response, PCD is carried out in a regulated process that generally confers advantages during an organism's life cycle.

Sperm and egg from skin cells eventually might be used for reproductive purposes, enabling parenthood at any age using tissue from either the living or dead.

Working copies of active genes — called messenger RNAs or mRNAs — are positioned strategically throughout living tissues, and their location often helps regulate how cells and tissues grow and develop.

That's an advantage for drug tests over flat - dish cell cultures currently used because it more accurately represents living tissue and more of the test cells can be kept alive by vessel - supplied nutrients.

The team found that people have large numbers of neural stem cells and progenitors early in life — an average of 1618 young neurons per square millimeter of brain tissue at birth.

Of the motivation behind the ground - breaking study, Miss Restrepo - Schild said: «I have always been fascinated by the human body, and want to prove that current technology could be used to replicate the function of human tissues, without having to actually use living cells.

The study of human astrocytes has faced issues related to access (samples of living tissue must be obtained from brain cancer or epilepsy surgeries or fetal tissue) and purification (breaking apart astrocytes away from other cells often killed them and many experiments ended in failure).

Cells reprogrammed in living mice (green) can contribute to both the placenta and body tissues of a developing mouse.

Cell regeneration is a biological feature of all living organisms with an important role in growth, wound healing, tissue repair and similar biological functions.