Sentences with phrase «liver cell injury»

An increase in ALT is highly specific to liver cell injury in dogs and cats.

Not exact matches

It can lead to substantial injury to the mother's liver, a breakdown of her red blood cells, and lowered platelet count,» Eleni Tsigas, Chief Executive Officer of the Preeclampsia Foundation, explains to Romper.

Large quantities of these reverted cells could be used to treat anything from spinal cord injury to liver damage without the risk of tissue rejection, said Robert Weinberg, a biologist at the Massachusetts Institute of Technology's Whitehead Institute for Biomedical Research and co-author of a study appearing in Cell.

Dr. Llovet and colleagues demonstrated that the expression of mutant IDH in the adult liver of genetically engineered mice impairs liver cell development and liver regeneration — a process in which the liver responds to injury — and increases the number of cells to form a tumor.

The research demonstrated that following injury, there is increased migration of inflammatory cells from blood to the liver, increasing IFNL3 secretion and liver damage.

Hepatitis researchers have long thought that immune cells sent by the body to attack virus - infected cells in the liver cause the acute liver injury associated with hepatitis A virus (HAV) and other hepatitis viruses.

Akassoglou and her colleagues thought they had a good candidate in the gene for the p75 neurotrophin receptor (p75NTR), a regulator of cell death in the brain that also switches on soon after liver injuries.

In some, the cells were always active; in others, such as the liver, they multiplied only when tissues sensed injury.

The liver then instructs white blood cells to go to the site of injury in the brain.

Because of the work of several other collaborators, Haughey says, his team knew that some sort of inflammation - promoting molecule was released from brain and targeted to the liver after brain injury to send immune system cells to the damaged area, but the identity of this go - between had been elusive for years.

Massive blood transfusions — defined as transfusing at least 10 units of red blood cells within 24 hours — are given to patients experiencing severe blood loss, often in response to traumatic injuries but also in the context of procedures like cardiovascular surgery or liver transplantation and even in some non-surgical patients.

«Under normal circumstances, myofibroblasts stimulate wound healing, but when there's an ongoing injury to an organ (e.g., the liver of a hepatitis C patient, the heart of a patient with high blood pressure, or the kidney of a patient with diabetes) these proteins clog up normal functioning,» said Humphreys, a Harvard Medical School associate professor at Brigham and Women's Hospital, who leads the Harvard Stem Cell Institute Kidney Program.

Research Interests: alcoholic liver disease; macrophages; C1q; apoptosis; fibrosis; liver disease; alcohol; Heme - oxygenase - 1; inflammation; necroptosis; high - fat diet; liver injury; fatty liver disease; complement; hepatocytes; alcoholic hepatitis; hepatic stellate cell; adiponectin; MIF; carbon tetrachloride

Adult stem / progenitor cells are present in many organs and tissues, e.g., bone marrow, teeth, heart, gut, kidney and liver, and remain quiescent for long period of time until activated by a disease or injury trigger.

Making use of cell and animal models, my laboratory group addresses some of the fundamental questions of how ethanol exposure injures the liver, with a goal ofidentifying the individual targets of ethanol - induced injury and the specific responses of the key cell types within the liver, as well as the integrated, organismal response to this ethanol - induced injury.

Differential contribution of complement receptor C5aR in myeloid and non-myeloid cells in chronic ethanol - induced liver injury in mice.

In particular, we are interested in the contributions of the innate immune system, including the resident macrophage in the liver (Kupffer cells) and the complement pathway, in the initiation and progression of ethanol - induced liver injury.

Mesenchymal stem cell (MSC)- derived exosomes mediate tissue regeneration in a variety of diseases including ischemic heart injury, liver fibrosis, and cerebrovascular disease.

I believe that injury and haemolysis can give false LFT readings because other cells, including muscle, contain some of the same enzymes as liver cells.

Stem Cell therapy is used for Degenerative Joint Disease, meniscal and ligament injuries, and research is being done for Diabetes and Liver and Kidney disease.