Mice engineered to lack REG3G and fed alcohol for eight weeks were more susceptible to bacterial migration from the gut to
the liver than normal mice who received the same amount of alcohol.
Not exact matches
That research showed that
mice on a
normal diet who were exposed to low doses of antibiotics throughout life, similar to what occurs in commercial livestock, packed on 10 to 15 percent more fat
than untreated
mice and had a markedly altered metabolism in their
liver.
REG3G - deficient
mice also developed more severe alcoholic
liver disease
than normal mice.
When the researchers injected extra copies of the betatrophin gene into the
liver of
normal mice, the animals» pancreases responded by making as much as 30 times more β cells
than usual.