Not exact matches
Instead
of slimming down, the
mice developed low blood sugar,
diabetic tendencies, and fatty
livers worthy
of pâté.
The U-M study explains how increased cAMP in fat cells promotes the secretion
of the hormone interleukin - 6, which signals the
liver to stop producing glucose — thus improving overall blood sugar levels in obese
diabetic mice.
They then inserted the DNA encoding this analogue into a virus that had been rendered harmless, incorporated the region
of the
liver cell that responds to glucose, and injected the modified virus into
diabetic mice and rats.
In our previous study we found that a high fat diet containing comparable amounts
of soybean oil to what Americans are currently consuming caused
mice to become obese,
diabetic and insulin resistant and to have large lipid droplets and hepatocyte ballooning in their
livers.