Sentences with phrase «living tumor cells»

«Capturing live tumor cells in the blood.»

Not exact matches

«For pro-life folk, imagine a country where it was illegal to remove a tumor, even if the tumor might kill the host, because the tumor is its own collection of living cells.

«Circulating tumor cells have the advantage that they are... intact living cells,» says Michael Kazinski, senior director and head of global product management for sample technologies at Qiagen in Hilden, Germany.

«Circulating tumor cells have the advantage that they are... intact living cells.»

In many patients diagnosed with LUAD, tumors cells have already spread to the brain, leading to decreased quality of life and low survival rates.

Using human - derived glioblastoma cells in a mouse models, researchers found that the modified high - fat, low - carbohydrate diet increased life expectancy by 50 percent while also reducing tumor progression by a similar amount.

«And in this study, we have formally demonstrated for the first time that these cells are compromised in living brain tumor patients.»

You have T cells for the rest of your life, so if the tumor reoccurs those T cells can mobilize themselves again against the tumor.

It tricks the cells into ending their lives in a controlled way, thereby reducing the size of the tumor.

The bacteria the group found, explains Straussman, live within the tumors, and even within the tumor cells.

In cancer, these switches inappropriately activate or silence important genes, such as those that regulate cell growth and life cycle, ultimately leading to tumors.

But, counter-intuitively, this mass cell death might be the very thing that makes the animals so long - lived: it could be a natural mechanism their bodies use to clear precancerous cells, stopping tumors in their tracks.

Until recently, Ain was renowned for a highly prized repository of 18 immortal cancer cell lines, which he developed by harvesting tissue from his patients» tumors after removal, carefully culturing them to everlasting life in vials.

At worst we would end up with a few little pebble tumors, small balls of abnormal cells that had exhausted their ability to grow, no more life - threatening than a mole or a small cyst.

Now a team of researchers in China has developed a new microfluidic chip that can quickly and efficiently segregate and capture live circulating tumor cells (CTCs) from a patient's blood, with potential applications for cancer screenings and treatment assessments.

Using tumor samples from the Women's Healthy Eating and Living clinical trial, researchers identified stem - like tumor cells as being characterized by low levels of the molecule p53 upregulated modulator of apoptosis (PUMA).

If they can be used in living tissue, they might eventually track cells in developing embryos, the immune system, or cancerous tumors.

«We conclude that KIF1B - β plays a key role in the decision between life and death for neural crest cells and tumors originating from the neural crest,» says Susanne Schlisio.

To overcome these problems, Min and his team developed a new modality to visualize glucose uptake activity inside single cells based on stimulated Raman scattering (SRS) imaging, and demonstrated its use in live cancer cells, tumor xenograft tissues, primary neurons and mouse brain tissues.

The regrowth of cancer stem cells is responsible for the drug resistance that develops in many breast tumors and the reason that for many patients, the benefits of chemo are short - lived.

The research team behind the new study previously discovered that genes mutated in some of the tumors play a central role in determining whether neural crest cells live or die.

Researchers have identified a group of immune system genes that may play a role in how long people can live after developing a common type of brain cancer called glioblastoma multiforme, a tumor of the glial cells in the brain.

The method gives researchers a glimpse of «what happens in the real life of a tumor,» says Cédric Blanpain, a stem cell researcher at the Université Libre de Bruxelles in Belgium.

Another is that the transplanted bits of tumor act nothing like cancers in actual human brains, Fine and colleagues reported in 2006: Real - life glioblastomas grow and spread and resist treatment because they contain what are called tumor stem cells, but tumor stem cells don't grow well in the lab, so they don't get transplanted into those mouse brains.

Treating the smoldering embers that surround the tumor rather than just mutant cells could make cancer a disease we can live with.

Northwestern University scientists now have demonstrated a simple but powerful tool that can detect live cancer cells in the bloodstream, potentially long before the cells could settle somewhere in the body and form a dangerous tumor.

The NanoFlare technology is the first genetic - based approach that is able to detect live circulating tumor cells out of the complex matrix that is human blood — no easy feat.

«We had a hunch that rapidly growing tumors can «outgrow» their blood supply, resulting in dead tumor cells that might spill their viral antigens amongst the living cancer cells,» said co-senior study author Arturo Casadevall, chair of Einstein's Microbiology & Immunology department.

While this approach has had some clinical success, in most cases, the immune response resulting from dendritic cell vaccines is short - lived and not robust enough to keep tumors at bay over the long run.

Furthermore, when injected into live animals, these aberrant cells form tumors.

«These findings further underscore the importance of the maternal microbes during early life and that our bacteria are an integrated component of our body physiology,» says Professor Sven Pettersson, the principal investigator at the Department of Microbiology, Tumor and Cell Biology.

About two - thirds of people with the germinal center subtype live for five years or more after diagnosis, while those with activated B - cell - like tumors have a poorer prognosis with current treatment regimes.

Gold nanotubes engineered to a specified length, modified surfaces, and to have other desirable characteristics showed expected abilities to enter tumor cells in laboratory studies, and to distribute to tissues within live mice as intended.

These so - called «living drugs» — injected T cells genetically modified to better recognize and kill tumor cells through a perpetual process of cell renewal and expansion — are revolutionizing cancer treatment, with the first two FDA approvals of such gene - altering therapies occurring in just the last two months.

Due to the high efficiency of establishing organoid models from different tissues and diseases, such as cancer, organoid technology allows the generation of large living biobanks of tumor organoids that are amenable for middle - throughput drug screens and may allow personalized therapy design, as a complement to cell line and xenograft - based drug studies (7,19).

Even if a therapy was able to kill one type of tumor cell, the others would still live and continue to grow.

In tumors, the clockwork genetic mechanisms that control the life cycle of cells are entirely disrupted, a fact that may hold the key to defeating cancer.

Researchers in the laboratory of Mikhail Shapiro, assistant professor of chemical engineering and Heritage Medical Research Institute Investigator, have invented a new method to link magnetic resonance imaging (MRI) signals to gene expression in cells — including tumor cells — in living tissues.

Cancer tumors, like other living cells, need to consume nutrients and oxygen to sustain themselves.

Once tumor cells strike out on their own and metastasize to new sites in the body, drugs and other therapies rarely do more than prolong a patient's life for a few years.

Combining genetics, live - imaging, laser ablation and computer simulations, we aim to analyze whether distinct or similar mechanisms can account for the common role of tumor suppressors and proto - oncogenes in cell - cell contact regulation.

In 2000, our founder Professor Yoram Palti sought to leverage his expertise in biophysics to develop a new way to treat cancer that would destroy tumor cells while sparing healthy tissue and avoiding many of the life - altering side effects of existing cancer therapies.

In essence, Knudson, far ahead of his time (and ahead of his own hard data) hypothesized that some genes» normal role in life is to behave as anticancer or tumor - suppressor genes that keep cell division under healthy control.

The most famous, oldest, and most commonly used immortal cell line, dubbed HeLa, originated in a tumor sample taken from an African - American woman, Henrietta Lacks, who is the subject of the recent book The Immortal Life of Henrietta Lacks.9 The tumor cells, harvested at Johns Hopkins Hospital, gave rise to the eponymous HeLa cell line which researchers have used continuously since her death in 1951 for numerous experiments, including Jonas Salk's development of the polio vaccine.

Since these experiments were only performed on cancer cells in test tubes, the researchers took the next step and ran tests on breast cancer tumors in live mice.

Cancer shortens the lives of nearly half of all dogs and cats in the U.S. Cancer in pets occurs when the body's immune system can not stop cells from replicating at an abnormally fast, disorderly pace and forming a mass known as a tumor.

Radiation therapy can help extend the lives of affected dogs, but also is ineffective against tumor cells that have metastasized.

By doing so, we hope that this would improve the accuracy of cancer diagnoses and treatment recommendations we make for dogs with mast cell tumors and other cancers, improving their quality of life and lifespan.

Mast cells contain granules filled with substances which can be released into the bloodstream and potentially cause systemic problems, including stomach ulceration and bleeding, swelling and redness at and around the tumor site, and potentially life - threatening complications, such as a dangerous drop in blood pressure and a systemic inflammatory response leading to shock.

Today's effective treatment options can actually cure the disease by killing off the abnormal tumor cells while leaving the normal thyroid cells undamaged, resulting in a normal life span for many affected cats.