The cells, or clones, that multiplied in these CGD patients had gene insertions in three
locations near genes involved in cell proliferation.
Not exact matches
C. renhardtii had similar
genes near but outside its MT. Like so much else, it seems sex cells are all about
location,
location,
location (Science, vol 328, p 351).
The model requires the ecRNA to stay
near or at the
gene after synthesis in order to regulate the methyltransferases just at that
gene location.
To evaluate the global human methylome in adipose tissue, we calculated the average level of methylation for all sites divided into groups based on either their
location in relation to the
nearest gene (Fig. 2A) or the
location in relation to CpG islands (Fig. 2B)(24).