Sentences with phrase «long coding sequence»

This allele deletes 433 bp of a 1083 bp long coding sequence, rendering the GPCR non-functional.

Not exact matches

It starts with a long DNA strand — called a scaffold — that has a precise sequence of the four molecular units, or nucleotides, dubbed A, C, G, and T, with which DNA spells out its genetic code.

With such long stretches of DNA, Hung and his team could assess the extent to which the sequences of DNA code in the genes in the three specimens varied from bird to bird.

First the two researchers narrowed the possible location of the lin - 4 gene to a sequence of DNA 700 nucleotides long, about one - third the size of a typical protein - coding gene.

Sequencing devices take long strings of a person's DNA and randomly chop them into small pieces that can be individually analyzed to determine their sequence of letters from the genetic code (A, C, G and T representing the four key components of DNA that code for protein production in living organisms: adenine, cytosine, guanine and thymine).

There, with help from Wasser and his colleagues in Seattle, geneticist Al Roca sequenced introns — vestigial sections of DNA from the nucleus that accumulate mutations quickly because they don't code for any physical traits — and confirmed that forest and savanna elephants diverged at least 2.6 million and probably more than 3 million years ago — long enough to render them separate species.

DNA sequencers can not sequence long pieces of DNA, so the extracted DNA molecules were sheared to different sized fragments in a controlled manner such that when they are sequenced they can be reassembled computationally by matching overlapping codes in the reads — creating long sequences of the genetic code.

- Scientists have long been reading the code of life — the genome — , as a sequence of letters but now researchers have also started exploring its three - dimensional organisation.

The remaining cassette can invert as long as Cre remains expressed; once Cre is removed from the system, the fluorescent protein whose coding sequence is closest to the promoter will be expressed.

HAR1 does not code for a protein but for a long RNA, a type of molecule that guides proteins or modulates their expression.5 We predicted that the HAR1 RNA could fold into a three - dimensional structure because its conserved sequence has palindromic regions that pair up to form a series of interconnected «stems» that look like ladders — think of an untwisted DNA double helix.

We additionally evaluated a collection of new de novo long - read haploid assemblies and conclude that although the new assemblies compare favorably to the reference with respect to continuity, error rate, and gene completeness, the reference still provides the best representation for complex genomic regions and coding sequences.