In a perspective in The Journal of the American Medical Association, the experts highlight innovations that could significantly shorten the typical decades -
long vaccine development timeline.
Not exact matches
Cheap, single - dose
vaccines made of live weakened bacteria that confer
long - term immunity could change that, and are in «advanced stages of
development», says Matthew Waldor of Harvard Medical School in Boston.
«While awaiting
development of new
vaccines that will provide
longer - lasting protection against pertussis, we should consider alternate Tdap immunization strategies for adolescents.»
With more than 5,000 genes and a maddeningly complicated life cycle, the malaria parasite (Plasmodium falciparum) has routinely outmaneuvered the human immune system and
long frustrated
vaccine development efforts.
«This gp41 protein from the virus envelope is not an absolute novelty in the
long history of anti HIV
vaccine development,» says Alexandru Rafila, Chairman of the Romanian Society for Microbiology in Bucharest.
In October, as senior citizens and others at high risk from flu waited in
long lines for shots after half of the United States»
vaccine supply for the season was lost, epidemiologists were already on high alert because of an ominous
development halfway around the world.
He and his colleagues have made significant discoveries about how immune memory cells are created and how
long they survive; understanding these mechanisms is crucial to the
development of
vaccines for HIV and other infectious agents.
Vaccine development for DENV is challenging in that the vaccine must induce long - lasting immunity against all four DENV serotypes (DENV1 - 4), as pre-existing immunity against a heterologous serotype may contribute to severe dengue disease (DHF
Vaccine development for DENV is challenging in that the
vaccine must induce long - lasting immunity against all four DENV serotypes (DENV1 - 4), as pre-existing immunity against a heterologous serotype may contribute to severe dengue disease (DHF
vaccine must induce
long - lasting immunity against all four DENV serotypes (DENV1 - 4), as pre-existing immunity against a heterologous serotype may contribute to severe dengue disease (DHF / DSS).
See David A. Garber and Mark B. Feinberg, «AIDS
Vaccine Development: The
Long and Winding Road,» AIDS Reviews, Vol.
While erythrocyte invasion is a rapid process, the brief extracellular exposure of merozoites outside of their intra-erythrocytic niche places them in direct contact with host antibodies, which contribute to naturally acquired immunity to malaria [8, 9]; therefore, merozoite cell surface and secreted proteins have
long been considered attractive targets for rational
vaccine development.
They are among 34 groups in Florida to receive a piece of $ 25 million in state funds that Gov. Rick Scott OK's last year for Zika
vaccine development, testing methods and understanding the
long - term impact of the virus.
The government of the United States has
long championed AIDS
vaccine development, not only through its scientific agencies, but also through the U.S. Agency for International Developme
development, not only through its scientific agencies, but also through the U.S. Agency for International
DevelopmentDevelopment (USAID).
From the aqueducts of ancient Rome to the pyramids of ancient Egypt, the birth of the written word to the
development of
vaccines, humans have been inventing about as
long as they've been standing.
Since then I learned some techniques from an experienced Hollywood script
development exec, like starting with a one - sentence log line (the first sentence of my description of
Vaccine Nation above is one, a bit
long at 36 words) that captures the story, and then build the outline, including key dramatic steps, in three acts from there.
Modified live
vaccines can cause swift
development of
long - lasting immunity but may produce mild cases of illness.
After examining all data collected during the study, the researchers concluded that there is a connection between the administering of certain
vaccines (recombinant vs. inactivated rabies) and other injectable materials (e.g.,
long - acting corticosteroids) with sarcoma
development.
Once I came to the conclusion that there was no valid reason for most yearly pet
vaccines — and there was a possibility that
vaccines could trigger the
development of serious diseases — I felt I could no
longer work at a conventional veterinary clinic.
Morris Animal Foundation has a
long history of funding innovative research in feline virology, including studies that led to the
development of the first feline leukemia virus
vaccine.