Verma, whose team will publish its findings tomorrow in Nature, says the findings emphasize the need for
longer preclinical studies.
Not exact matches
Drew Pardoll, Glenn Dranoff, Elizabeth Jaffee, Hyam Levitsky, and colleagues conduct
preclinical studies showing that a vaccine composed of tumor cells irradiated and genetically modified to produce immune system growth factor GM - CSF (granulocyte - macrophage colony - stimulating factor)-- which would become known as the therapeutic cancer vaccine GVAX — could induce potent, specific, and
long - lasting anti-tumor immunity in multiple mouse tumor models.
While
preclinical studies suggest that this treatment may be effective,
long - lasting and well - tolerated, the
study now underway at Roswell Park marks the first time this strategy will be assessed in humans.
«Lithium,
long used in mental health as a highly effective mood stabiliser, has been on the radar as a potential disease modifying treatment for Alzheimer's disease with positive evidence from
preclinical studies and a number of small clinical trials.
Preclinical studies suggest that stress early in life can promote
long - term changes in multiple neurochemical systems (6, 7).