Sentences with phrase «longer than wild type»

A very neat paper shows that transgenic mice made to overexpress a certain hormone live much longer than wild type mice: The starvation hormone, fibroblast growth factor - 21, extends lifespan in mice.

Not exact matches

Rather than being a point in sequence - space, each such quasi-species» may be regarded as a cloud of such points, with high density in the region of the wild - type but with significant, long extensions in several directions.

As the mice aged, their motor performance on a rotarod test (which measures how long the mouse can remain on a rotating rod) became impaired and the length of their strides were significantly shorter than the wild type control mice.

The TGF - β mutants that Murphy also studied could reproduce far longer than wild - type (nonmutant) worms — but, unlike the IGF - 1 mutants, they didn't actually live any longer.

They showed that the flies missing Rh7 took significantly longer to adjust than the normal, wild type flies.

Among the survivors, they found two strains that lived longer than wild - type yeast.

Overall, the cytochrome B knock - out strain is much less virulent, and mice infected with it survive much longer than those with the wild - type strain.

In contrast, irradiated p21 - deficient mice survived longer than irradiated wild - type mice, and only one - third (32 %) of them developed tumors (Table 3 ⇓; Fig. 3 ⇓).

In Ames dwarrf, Snell Dwarf mice, Klotho mice, GHKO mice who have little IGF and GH; and live longer than wild - type; we see that indeed insulin and glucose / nutrient / energy pathways (which create oxidative stress through excessive nutrient via elevated glycation blood glucose creating high glycated albumin and hemoglobin), that aging is acted on by IGF through hormones, GFs, GHs, acting on insulin signals, which act on survival genes (DAF / SIRT / FOXO).

C. elegans mutants that live twice as long as wild - type worms in laboratory conditions typically die sooner than wild - type worms in a natural soil.