When researchers like Barzilai have looked for genes that might account for the extreme
longevity of the centenarians they study, they have typically found that the genes that stand out in one long - lived population do not do so in others.
Not exact matches
Still, when Barzilai and his colleagues questioned the near
centenarians as part
of their aging studies, the genetic determinant
of longevity took the researchers by surprise.
Their model successfully predicted exceptional
longevity in a different sample
of centenarians (individuals that live to age 100) with 77 percent accuracy.
Now scientists like Perls are sifting through millions
of DNA markers to spot the constellation
of longevity genes that's carried in every cell
of these
centenarians» bodies.
In order to find out whether this polymorphism is also associated with extreme
longevity, Spanish researchers performed an analysis
of the frequencies
of this polymorphism among
centenarians and healthy adults in two independent cohorts, by geographical regions and by ethnic groups.
The search for the genetic determinants
of extreme
longevity has been challenging, with the prevalence
of centenarians (people older than 100) just one per 5,000 population in developed nations.
To explore the genetic contribution, we undertook a genome - wide association study
of exceptional
longevity (EL) in 1055
centenarians and 1267 controls.
Garlic, onion, leeks, and shallots - In a study
of centenarians (people living over 100 years
of age), it was found that high garlic and onion consumption was one
of the factors that surveys revealed may have partial involvement in their
longevity.
All one can say is that Kitavans, with their diet
of far less junk food, higher (cellulose) vegetables, high MCTs, lower protein, that may help result in short and lean stature likely secondary to lower IGF - 1and mTOR (known
longevity factors in animals), with their less stressed lifestyle gives them low rates
of heart disease and diabetes but with only an average lifespan with few
centenarians, that may likely be despite eating starches than because
of it.
«A cross-section analysis
of FT3 age - related changes in a group
of old and oldest - old subjects, including
centenarians» relatives, shows that a down - regulated thyroid function has a familial component and is related to
longevity»
Longevity researchers (11) have long searched for the magic common denominators that might explain the extended life spans
of centenarians.