Sentences with phrase «looks change from year to year»

Also, signature looks change from year to year.

Not exact matches

And, that could be anything from, are there other people from the university that I attend who work here, could I talk to them, to what does it look like to change jobs in a couple years after I've been successful on my first project, to how long do people stay in this office?

We've made many changes to it over the years as we've learned from our experiences, and we're always looking for ways to make it better.»

More from The New York Times: Wall Street Firm Despite US Shutdown Japan Sales Tax to Increase Next Year, Abe Says An Ex-Trader, Now a Sociologist, Looks at the Changes in Goldman

Actual results and the timing of events could differ materially from those anticipated in the forward - looking statements due to these risks and uncertainties as well as other factors, which include, without limitation: the uncertain timing of, and risks relating to, the executive search process; risks related to the potential failure of eptinezumab to demonstrate safety and efficacy in clinical testing; Alder's ability to conduct clinical trials and studies of eptinezumab sufficient to achieve a positive completion; the availability of data at the expected times; the clinical, therapeutic and commercial value of eptinezumab; risks and uncertainties related to regulatory application, review and approval processes and Alder's compliance with applicable legal and regulatory requirements; risks and uncertainties relating to the manufacture of eptinezumab; Alder's ability to obtain and protect intellectual property rights, and operate without infringing on the intellectual property rights of others; the uncertain timing and level of expenses associated with Alder's development and commercialization activities; the sufficiency of Alder's capital and other resources; market competition; changes in economic and business conditions; and other factors discussed under the caption «Risk Factors» in Alder's Annual Report on Form 10 - K for the fiscal year ended December 31, 2017, which was filed with the Securities and Exchange Commission (SEC) on February 26, 2018, and is available on the SEC's website at www.sec.gov.

Following is a look at how blue collar workers in a number of occupations, from food preparation workers to power plant operators, could see their taxes change next year if the tax plan becomes law.

Looking at a simple asset allocation, a theoretical allocation to long - dated U.S. bonds (+20 years) fluctuates from as low as 3 % to as high as 25 % based on changes to the risk model, i.e. correlation of different asset classes.

Fed watchers had been looking for the language to change from «this year,» as indicated following the June meeting, to something more immediate.

Factors that could cause or contribute to actual results differing from our forward - looking statements include risks relating to: failure of DBRS to rate the Notes at the anticipated ratings levels, which is a closing condition, or at all; changes in the financial markets, including changes in credit markets, interest rates, securitization markets generally and our proposed securitization in particular; the willingness of investors to buy the Notes; adverse developments regarding OnDeck, its business or the online or broader marketplace lending industry generally, any of which could impact what credit ratings, if any, are issued with respect to the Notes; the extended settlement cycle for the scheduled closing on April 17, 2018, which may exacerbate the foregoing risks; and other risks, including those described in our Annual Report on Form 10 - K for the year ended December 31, 2017 and in other documents that we file with the Securities and Exchange Commission from time to time which are or will be available on the Commission's website at www.sec.gov.

Forward - looking statements may include, among others, statements concerning our projected adjusted income (loss) from operations outlook for 2018, on both a consolidated and segment basis; projected total revenue growth and global medical customer growth, each over year end 2017; projected growth beyond 2018; projected medical care and operating expense ratios and medical cost trends; our projected consolidated adjusted tax rate; future financial or operating performance, including our ability to deliver personalized and innovative solutions for our customers and clients; future growth, business strategy, strategic or operational initiatives; economic, regulatory or competitive environments, particularly with respect to the pace and extent of change in these areas; financing or capital deployment plans and amounts available for future deployment; our prospects for growth in the coming years; the proposed merger (the «Merger») with Express Scripts Holding Company («Express Scripts») and other statements regarding Cigna's future beliefs, expectations, plans, intentions, financial condition or performance.

A report for the Rio +20 climate change conference last year, «Leadership in a Rapidly Changing World,» interviewed top CEOs from multinational firms to determine what skills they are looking for when hiring.

Private - equity firms generally look for companies they believe investors will perceive differently five to seven years from now because of changes they can put in place.

Installed caps plus snapback hats ended up both donned over the years around baseball as teams had the capacity to change their particular look coming from year to year.

Yep you are right, I moved down here in the state of Mississippi, north of Crystal Springs from Chicago when I was ten years old but still I visit once in a while, now it's twenty years and sad to not much has change, like the parts you said about non-whites discrimatory or rasicts at other non-whites, when I went to school here they treated me as a alien from another galaxy, they pick at my voice cause I didn't had that southern dialog, unlike them I said my words correctly, but not just me, they even hated at others who had better intelect I am not picking at them, It is what I went through all these years, Mississippi and mainly this small town of Crystal Springs see America in a crazy awful view, They don't like difference that even within they own race, ther not that politcal, when some one say God they got there vote, I don't to say much to waste your time, I still remember when I was ten years old I had a constanct back ground check on me to see were I really come from evn though I had the paper saying Chicago Illinois barely no jobs but a church on every street for a town barely under five Thousand, till this very day, they look at me like I am a alien, did you ever had that experiance down here damn my keybroad mess up,

A recent study from researchers at Oxford University published in the medical journal The Lancet looked at how changing weather patterns will affect the planet's ability to grow enough food to adequately feed the global population, and the results are terrifying: They predicted that because of large scale agricultural changes, 247,970 could die in China alone by the year 2050.

Having changed from a very unhealthy diet two years ago I now look to your recipes for inspiration most days.

They are a wonderful change of pace from tradional sufgayniot and I am looking forward to adding them to my schedule of chanukkah frying this year.

So, to continue my series of looking back and seeing how nothing has changed, this article from two years ago shows that Arsene Wenger complaining about the Arsenal fans affecting the players is nothing new.

Look at how the players have been changing over the years in our defense from squillaci and djorou to vermaelin koscielny mustafi etc but the problems still persist.

nice to see you crawl out of your hole just in time to offer your 2 cents worth once again... unlike yourself I started following this team long before Wenger arrived on the scene and will continue to do so long after he's gone... in his earlier years I admired the cerebral elements he brought to the EPL, which at that point was more brutish than beautiful, and I respected the seemingly tireless efforts of Arsene, Dein & staff to uncover and develop talent without sacrificing the product on the field... likewise I appreciated that such a youthful manager wasn't afraid to bring strong personalities and / or world - class players into the fold without being fearful of how said players would potentially undermine and / or dilute his authority... unfortunately this all changed about 10 years ago and culminated in the removal of all our greatest players, both young and old, without any real replacements coming in... from Henry to RVP to Fabergas and Nasri, it was easy to see that this club was no longer interested in competing at the highest levels... instead of being honest, minus the ridiculous claims regarding the new stadium, Wenger chose to side with management and in doing so became the «front man» for this corporation pretending to be a world - class soccer club... without the «front man» this organization would have been exposed numerous years earlier, so his presence was imperative if the facade was to continue... it's for this reason and more that I despise what this once great man and Kroenke has done to my beloved club... the gutless, shameful and manipulative way they have treated the fans, like myself, is largely indefensible and this is why I felt it necessary to start offering my opinion in a public format... trust me, I resisted the temptation for many years but as long as the same shit continues to exist I will voice my opinions and if you don't like it maybe you should look for a different team to pretend to follow

I'm so sick of people telling those of us who are disgruntled fans to relax and give this club time to correct itself... for anyone who believes that taking a wait - and - see approach is appropriate at this juncture they should take a good long look at themselves in the mirror because they are a big part of the problem... no other «big» club's fans would stand for this shit for nearly as long as we have... think about it, we've witnessed a changing of the guard at every major club in England, Spain, France and Germany in the last several years because those «big» clubs failed to live up to expectations (Barcelona, Real Madrid, Bayern, PSG, Chelsea, ManU, ManCity etc...)... for some reason, many fans have become as fragile as our current manager, believing that there couldn't possibly be a suitable replacement, even though everyone of these clubs have found multiple replacements and still achieved far more than our club... this mindset has been created by an organization that has been milking it's fans, telling countless lies (no world class players available) and lowering expectations every since they rolled out the biggest lie of all: that we couldn't spend because of the new stadium but once it was paid off we could compete with any team in the world... this organization is rotting from the inside out and if we don't demand that those in charge put soccer first this despicable behaviour won't end with Wenger's ridiculous 2 year contract... I think the real fear isn't that a suitable replacement doesn't exist, but that this organization is so money hungry and poorly mismanaged that we will sink even lower by choosing our next coach the same way they choose our players, on the cheap... even so, we need to see what mustache will do if left to his own devices so he will have to show his true colours... only then can we purge this club and start anew

Arsenal Fans are most afraid fans ever, If Wenger leaves we will never be great again, LOL Everyone is looking Swansea game, look Arsenal from different angle, we are in this position last 9 years, we are not able to beat big teams, and how can someone blame players LOL, i ve never seen that player is sacked, we fans are afraid of change, and that is normal, but change will come, like it or not, Wenger getting new contract is biggest mistake, its so obvious that he cant do his job on high level, he can keep arsenal in top 4 but never win it again, so ask yourself, do you want every year to lie yourself about winning or accept mediocre, your choice!!!

This is an incredibly difficult question to answer for a variety of reasons, most importantly because over the years our once vaunted «beautiful» style of play has become a shadow of it's former self, only to be replaced by a less than stellar «plug and play» mentality where players play out of position and adjustments / substitutions are rarely forthcoming before the 75th minute... if you look at our current players, very few would make sense in the traditional Wengerian system... at present, we don't have the personnel to move the ball quickly from deep - lying position, efficient one touch midfielders that can make the necessary through balls or the disciplined and pacey forwards to stretch defences into wide positions, without the aid of the backs coming up into the final 3rd, so that we can attack the defensive lanes in the same clinical fashion we did years ago... on this current squad, we have only 1 central defender on staf, Mustafi, who seems to have any prowess in the offensive zone or who can even pass two zones through so that we can advance play quickly out of our own end (I have seen some inklings that suggest Holding might have some offensive qualities but too early to tell)... unfortunately Mustafi has a tendency to get himself in trouble when he gets overly aggressive on the ball... from our backs out wide, we've seen pace from the likes of Bellerin and Gibbs and the spirited albeit offensively stunted play of Monreal, but none of these players possess the skill - set required in the offensive zone for the new Wenger scheme which requires deft touches, timely runs to the baseline and consistent crossing, especially when Giroud was playing and his ratio of scored goals per clear chances was relatively low (better last year though)... obviously I like Bellerin's future prospects, as you can't teach pace, but I do worry that he regressed last season, which was obvious to Wenger because there was no way he would have used Ox as the right side wing - back so often knowing that Barcelona could come calling in the off - season, if he thought otherwise... as for our midfielders, not a single one, minus the more confident Xhaka I watched played for the Swiss national team a couple years ago, who truly makes sense under the traditional Wenger model... Ramsey holds onto the ball too long, gives the ball away cheaply far too often and abandons his defensive responsibilities on a regular basis (doesn't score enough recently to justify): that being said, I've always thought he does possess a little something special, unfortunately he thinks so too... Xhaka is a little too slow to ever boss the midfield and he tends to telegraph his one true strength, his long ball play: although I must admit he did get a bit better during some points in the latter part of last season... it always made me wonder why whenever he played with Coq Wenger always seemed to play Francis in a more advanced role on the pitch... as for Coq, he is way too reckless at the wrong times and has exhibited little offensive prowess yet finds himself in and around the box far too often... let's face it Wenger was ready to throw him in the trash heap when injuries forced him to use Francis and then he had the nerve to act like this was all part of a bigger Wenger constructed plan... he like Ramsey, Xhaka and Elneny don't offer the skills necessary to satisfy the quick transitory nature of our old offensive scheme or the stout defensive mindset needed to protect the defensive zone so that our offensive players can remain aggressive in the final third... on the front end, we have Ozil, a player of immense skill but stunted by his physical demeanor that tends to offend, the fact that he's been played out of position far too many times since arriving and that the players in front of him, minus Sanchez, make little to no sense considering what he has to offer (especially Giroud); just think about the quick counter-attack offence in Real or the space and protection he receives in the German National team's midfield, where teams couldn't afford to focus too heavily on one individual... this player was a passing «specialist» long before he arrived in North London, so only an arrogant or ignorant individual would try to reinvent the wheel and / or not surround such a talent with the necessary components... in regards to Ox, Walcott and Welbeck, although they all possess serious talents I see them in large part as headless chickens who are on the injury table too much, lack the necessary first - touch and / or lack the finishing flair to warrant their inclusion in a regular starting eleven; I would say that, of the 3, Ox showed the most upside once we went to a back 3, but even he became a bit too consumed by his pending contract talks before the season ended and that concerned me a bit... if I had to choose one of those 3 players to stay on it would be Ox due to his potential as a plausible alternative to Bellerin in that wing - back position should we continue to use that formation... in Sanchez, we get one of the most committed skill players we've seen on this squad for some years but that could all change soon, if it hasn't already of course... strangely enough, even he doesn't make sense given the constructs of the original Wenger offensive model because he holds onto the ball too long and he will give the ball up a little too often in the offensive zone... a fact that is largely forgotten due to his infectious energy and the fact that the numbers he has achieved seem to justify the means... finally, and in many ways most crucially, Giroud, there is nothing about this team or the offensive system that Wenger has traditionally employed that would even suggest such a player would make sense as a starter... too slow, too inefficient and way too easily dispossessed... once again, I think he has some special skills and, at times, has showed some world - class qualities but he's lack of mobility is an albatross around the necks of our offence... so when you ask who would be our best starting 11, I don't have a clue because of the 5 or 6 players that truly deserve a place in this side, 1 just arrived, 3 aren't under contract beyond 2018 and the other was just sold to Juve... man, this is theraputic because following this team is like an addiction to heroin without the benefits

Arsenal have changed their formation from a classic 442 to more of a 4231 over the years, but our current three at the back system looks revolutionary for the Gunners.

This is not about LOVE or HATE I don't hate the man neither love him, used to admire him though, unfortunately and this is an undeniable fact, he has lost the Compass, is not just about the transfers, POOR TACTICS, FAVOURING PLAYERS that underperform, believing he can switch Players from their natural position, POOR RESULTS against TOP CONTENDERS (while Newcastle, Sunderland, SPUDS and other bottom feeders made MAUREEN look helpless) I did not wake up one morning realizing all these facts, this has been happening for years now and his results are the proof that he either change or he should retire honorably and let AFC start a new era post WENGER.

Evans also saw an offer to train with former club Sheffield United withdrawn last year after pressure from club sponsors and ambassadors led to the Blades changing their position, and it is looking increasingly unlikely that he will be able to return to professional football.

look we knew chelski would be stronger this season and man city would be up there... we have known for 2 years that we lack a strong DM and a lethal strike force... as with case of ozil the frog has come up with half a solution with sanchez... and which will fail to bring the best from the quality players we have... will he change..

(3) this team is rotting from the inside out and it's going to take some unprecedented moves on the part of this board and the fans to facilitate the necessary changes... this club must rid itself of it's absentee billionaire landlord before we become just another sporting wasteland in this man's collection of flailing clubs... when this is done it will expose just what exactly has been going on behind the scenes and I'm afraid of what will be uncovered because if Wenger's business model is as antiquated as his football philosophy it could look an awful lot like and old Monty Python sketch in the backroom... we need to replace the owner with someone who actually cares about this club and isn't afraid to wear their emotions on his or her sleeves or spend their own money to achieve greatness... this new owner needs to find someone who represents the same sort of cutting edge that Wenger represented in his early years then pair that individual with someone who knows how to conduct transfers in the modern era... then and only then will we find a way to escape the malaise that has permeated our once storied club for way too many years

Time for some brutal honesty... this team, as it stands, is in no better position to compete next season than they were 12 months ago, minus the fact that some fans have been easily snowed by the acquisition of Lacazette, the free transfer LB and the release of Sanogo... if you look at the facts carefully you will see a team that still has far more questions than answers... to better show what I mean by this statement I will briefly discuss the current state of affairs on a position - by - position basis... in goal we have 4 potential candidates, but in reality we have only 1 option with any real future and somehow he's the only one we have actively tried to get rid of for years because he and his father were a little too involved on social media and he got caught smoking (funny how people still defend Wiltshire under the same and far worse circumstances)... you would think we would want to keep any goaltender that Juventus had interest in, as they seem to have a pretty good history when it comes to that position... as far as the defenders on our current roster there are only a few individuals whom have the skill and / or youth worthy of our time and / or investment, as such we should get rid of anyone who doesn't meet those simple requirements, which means we should get rid of DeBouchy, Gibbs, Gabriel, Mertz and loan out Chambers to see if last seasons foray with Middlesborough was an anomaly or a prediction of things to come... some fans have lamented wildly about the return of Mertz to the starting lineup due to his FA Cup performance but these sort of pie in the sky meanderings are indicative of what's wrong with this club and it's wishy - washy fan - base... in addition to these moves the club should aggressively pursue the acquisition of dominant and mobile CB to stabilize an all too fragile defensive group that has self - destructed on numerous occasions over the past 5 seasons... moving forward and building on our need to re-establish our once dominant presence throughout the middle of the park we need to target a CDM then do whatever it takes to get that player into the fold without any of the usual nickel and diming we have become famous for (this kind of ruthless haggling has cost us numerous special players and certainly can't help make the player in question feel good about the way their future potential employer feels about them)... in order for us to become dominant again we need to be strong up the middle again from Goalkeeper to CB to DM to ACM to striker, like we did in our most glorious years before and during Wenger's reign... with this in mind, if we want Ozil to be that dominant attacking midfielder we can't keep leaving him exposed to constant ridicule about his lack of defensive prowess and provide him with the proper players in the final third... he was never a good defensive player in Real or with the German National squad and they certainly didn't suffer as a result of his presence on the pitch... as for the rest of the midfield the blame falls squarely in the hands of Wenger and Gazidis, the fact that Ramsey, Ox, Sanchez and even Ozil were allowed to regularly start when none of the aforementioned had more than a year left under contract is criminal for a club of this size and financial might... the fact that we could find money for Walcott and Xhaka, who weren't even guaranteed starters, means that our whole business model needs a complete overhaul... for me it's time to get rid of some serious deadweight, even if it means selling them below what you believe their market value is just to simply right this ship and change the stagnant culture that currently exists... this means saying goodbye to Wiltshire, Elneny, Carzola, Walcott and Ramsey... everyone, minus Elneny, have spent just as much time on the training table as on the field of play, which would be manageable if they weren't so inconsistent from a performance standpoint (excluding Carzola, who is like the recent version of Rosicky — too bad, both will be deeply missed)... in their places we need to bring in some proven performers with no history of injuries... up front, although I do like the possibilities that a player like Lacazette presents, the fact that we had to wait so many years to acquire some true quality at the striker position falls once again squarely at the feet of Wenger... this issue highlights the ultimate scam being perpetrated by this club since the arrival of Kroenke: pretend your a small market club when it comes to making purchases but milk your fans like a big market club when it comes to ticket prices and merchandising... I believe the reason why Wenger hasn't pursued someone of Henry's quality, minus a fairly inexpensive RVP, was that he knew that they would demand players of a similar ilk to be brought on board and that wasn't possible when the business model was that of a «selling» club... does it really make sense that we could only make a cheeky bid for Suarez, or that we couldn't get Higuain over the line when he was being offered up for half the price he eventually went to Juve for, or that we've only paid any interest to strikers who were clearly not going to press their current teams to let them go to Arsenal like Benzema or Cavani... just part of the facade that finally came crashing down when Sanchez finally called their bluff... the fact remains that no one wants to win more than Sanchez, including Wenger, and although I don't agree with everything that he has done off the field, I would much rather have Alexis front and center than a manager who has clearly bought into the Kroenke model in large part due to the fact that his enormous ego suggests that only he could accomplish great things without breaking the bank... unfortunately that isn't possible anymore as the game has changed quite dramatically in the last 15 years, which has left a largely complacent and complicit Wenger on the outside looking in... so don't blame those players who demanded more and were left wanting... don't blame those fans who have tried desperately to raise awareness for several years when cracks began to appear... place the blame at the feet of those who were well aware all along of the potential pitfalls of just such a plan but continued to follow it even when it was no longer a financial necessity, like it ever really was...

Ivanovic has always been a rock in Chelsea's defense and that doesn't look likely to change anytime soon, not sure if you've seen Chelsea's matches this year but he has gotten off to a blistering start and was probably Chelsea's best player vs Leicester (this is the time where we usually bash Leicester and say «Oh they are a newly promoted club» but truth be told we escaped with a point from playing them if we are being unbiased)

A self - deprecating NCAA is a welcome switch from the previously smug organization that has only been moved to meaningful action in the recent past by federal court decisions (the ban on cost - of - attendance stipends became illegal once the NCAA got whipped in O'Bannon vs. NCAA) and terrible PR (Connecticut guard Shabazz Napier made the schools look silly with their food rules by speaking out during a tournament that makes $ 770 million a year for the NCAA in television revenue, hence the unlimited meals rule change).

you could have a point there My dear old dad was having radio therapy last summer and the guy who drove him to his appointments has a 15 year old son in the youth team who quiet freely stated that in the dressing room the rumour is that Theo has lost his bottle and does nt want to injured again.Thing is he was in my opinion NEVER really that good he is great if he has no time to think about his last touch but give him that extra second and he fluffs his lines continuously He is also really really lazy and he really looks like he just cant be bothered and AW giving him a contract extension AND wage increase just shows how far from reality the changing room has become.

At the midpoint of the season just 7 points separate 10th from the relegation zone and the title race looks set to be one of the tightest battles in years after a week in which top spot changed hands three times, so many teams could be looking to spend big to achieve their goals.

With the programme changing year upon year, we hope you enjoy looking back through the club's programme history, as you reminisce about the incredible journey from the Goldstone Ground to the Amex.

From a groundbreaking invention that changed the way strollers look and work, to an established design icon, the Bugaboo Cameleon ³ has been making parenting easier for more than 15 years.

It is really lovely to look at these from previous years and see how much the kids have grown and changed in that time.

By Education Week News (blog) From youth - concussion laws to sport - specific rule changes, the landscape of youth sports looks dramatically different from where it was even five years From youth - concussion laws to sport - specific rule changes, the landscape of youth sports looks dramatically different from where it was even five years from where it was even five years ago.

However, if we look at the places that had local elections on the same boundaries last year and this year (combining district wards to make county divisions), the UKIP change since 2012 is equally strongly correlated with both the Conservative and Labour change, suggesting that relative to last year both parties suffered equally from UKIP progress.

Details of those changes will be announced later this year after they have been approved by Council... Similarly, we are also looking again at our international qualification... ADIT continues to be incredibly successful with nearly 600 existing graduates and over 2000 students from over 100 countries.

The other, more trustworthy method is to look at how changes in CO2 have affected past climate, from the recent past to millions of years ago.

Looking at shifts in Manley's winter temperatures from year to year, he says, gives a good reading of important natural cycles that influence climate, such as changes in ocean circulation like the North Atlantic Oscillation.

The oldest studied rodent fauna in this work, which inhabited the Iberian Peninsula from twelve million years ago, progressively shifted north looking for humid environments to survive climate change that caused prominent dry and cold environments in central Iberia.

«Now that we know how these factors changed from the ice age to today,» Marcott says, «we thought, if we really want to put the future in perspective, we can't look out just 300 years.

A geneticist at the University of Illinois at Urbana - Champaign, she travels to Siberia each year to collect blood from hundreds of silver foxes to look for genetic changes that produce tame and aggressive behaviors.

Seeing the sharp declines in parts of the ocean I have come to know and love reminds me that as we look into new ways to protect our planet from climate change, we need to look again at the natural machinery that already works, that developed over four and a half billion years, and do everything we can to restore its functions.

To look at the rate of change in working memory in relation to different measures of socioeconomic status, the researchers studied more than three hundred 10 - through 13 - year - olds from urban public and parochial schools over four yearTo look at the rate of change in working memory in relation to different measures of socioeconomic status, the researchers studied more than three hundred 10 - through 13 - year - olds from urban public and parochial schools over four yearto different measures of socioeconomic status, the researchers studied more than three hundred 10 - through 13 - year - olds from urban public and parochial schools over four years.

«When we look to the fossil record, from hundreds of millions of years ago to near present day, we see episodes of climatic change and biological upheaval, and we see similar patterns.»

New measurements by NASA's Goddard Institute for Space Studies indicate that 2012 was the ninth warmest year since 1880, and that the past decade or so has seen some of the warmest years in the last 132 years.One way to illustrate changes in global atmospheric temperatures is by looking at how far temperatures stray from «normal», or a baseline.

For the study, Mahony and co-author Alex Cannon from Environment and Climate Change Canada looked at historical observations going back to 1901 and global climate model projections to the year 2100.

The Search for Extraterrestrial Intelligence has always looked for an anomaly in the persistent cosmic background chatter — a change perhaps in the intensity of a signal that can be taken as a sign that a transmission might be a message to us earthlings from other intelligent beings.Each year, medical researchers who gather at the Alzheimer's Association International Conference search for something similar as they weigh reports of the complex biology of the human brain for some sign that a drug might actually change the relentless course of the disease.