However, the betting public seems to view that
loss as an aberration, not a trend, with more than 6 out of 10 spread bets picking New Orleans to bounce back and win by at least 9 points in the SuperDome.
Given their typical age of onset, a broad range of mental disorders are increasingly being understood
as the result of
aberrations of developmental processes that normally occur in the adolescent brain.4 — 6 Executive functioning, and its neurobiological substrate, the prefrontal cortex, matures during adolescence.5 The relatively late maturation of executive functioning is adaptive in most cases, underpinning characteristic adolescent behaviours such
as social interaction, risk taking and sensation seeking which promote successful adult development and independence.6 However, in some cases it appears that the delayed maturation of prefrontal regulatory regions leads to the development of mental illness, with neurobiological studies indicating a broad deficit in executive functioning which precedes and underpins a range of psychopathology.7 A recent meta - analysis of neuroimaging studies focusing on a range of psychotic and non-psychotic mental illnesses found that grey matter
loss in the dorsal anterior cingulate, and left and right insula, was common across diagnoses.8 In a healthy sample, this study also demonstrated that lower grey matter in these regions was found to be associated with deficits in executive functioning performance.