Sentences with phrase «loss of these cells»

This is because T1D — a disease that affects an estimated 1.5 million Americans and was previously known as juvenile diabetes — is the result of the unexplained loss of cells in the pancreas that produce insulin.

Traditional fed - batch culture platforms support protein production for max 3 — 4 weeks, with rapid loss of cell viability caused by the accumulation of waste and inconsistent nutrient availability.

We propose that the age - related decline in the regenerative behavior of glial cells is caused by loss of cell - to - cell communication and changes in the internal gene expression of glia cells.

This pathway also could be relevant in conditions involving loss of cells that make this insulation, like multiple sclerosis.»

Researchers observed a 50 percent loss of cells when they injected normal mice with an agent that selectively kills dopamine neurons of the substantia nigra (to emulate Parkinson's) semiweekly for five weeks.

«Damage or loss of these cells leads to plaque buildup within the arteries and eventually cardiovascular disease.

Functional damage to these photoreceptors, or pathological loss of the cells that bear them, results in inability to register light impinging on the retina — and is responsible for various types of visual impairment and certain forms of congenital blindness.

The most severe cytopathic effects were observed 48 hours after infection, with a larger number of rounded, swollen cells, more syncytium formation and pronounced loss of cell integrity, all of which denote cell death.

These changes are so fundamental that they lead to prominent alterations in cell shape and loss of cell polarity, alterations that ultimately affect the epithelial barrier,» explained d'Azzo.

«We found that mice that had been genetically engineered to produce human apoE4 lost a specific kind of cells and that loss of these cells correlated with the extent of learning and memory deficits,» said Yaisa Andrews - Zwilling, PhD, postdoctoral fellow and lead author of the study.

Starvation shifts the balance towards a net loss of cells, thus literally shrinking the animals («de-growth»).

In breast cancer, we adopted information theory to quantify spontaneous loss of cell phenotypic identity, which may be relevant to progression and resistance.

ps3 6 billion loss then theres the multi billion loss of cell cpu and the slowing tv and pc sales sony are screwed...

«Loss of cells in brain's memory center linked to schizophrenia: Deterioration of tiny brain region offers clues to onset of psychiatric disorder.»

In absence of IM30, thylakoid membranes are noticeably deteriorated, which can subsequently lead to loss of cell viability.

If this had been an attempt to clone a human being, would there have been 276 losses of cells and DNA material or 276 lost human lives?

Stem cells play an important role in the development of many organs, and the loss of these cells at birth could affect babies» later development, the researchers write.

For example, the loss of cell phone, video game privileges, or time with friends.

If researchers could reduce the loss of cells, they could one day treat two or even three times as many patients from the limited number of cadaver donors available, García noted.

Since beta cells do not regenerate, scientists have traditionally assumed that the loss of these cells is irreversible; indeed, diabetic patients require insulin injections for life.

But the loss of these cells is prevented by treatment with the CDK2 inhibitor kenpaullone (bottom).

However, current available treatments fail to address the loss of cells and cellular functions.

The upper images show two views of the mushroom - shaped cysts that result from the loss of cell adhesion in the nephron.

Since only limited replacement of astrocytes occurs in the brain, loss of these cells may cause serious damage.

The Federal Emergency Management Agency (FEMA) wrote in its 2013 National Preparedness report last week that during and immediately following Hurricane Sandy, «users sent more than 20 million Sandy - related Twitter posts, or «tweets,» despite the loss of cell phone service during the peak of the storm.»

Leveling Waddington: the emergence of direct programming and the loss of cell fate hierarchies

Currently, there is no treatment to prevent or slow the loss of these cells in dry AMD patients.

Now this latter element, it turns out that we have a real opportunity because as Dave Calkins and others have now demonstrated very beautifully in animal models, and we even have very good data now in humans; in glaucoma there's an injury that happens first, and it's the death or loss of the cell that happens later in the disease.

Loss of these cells is a common endpoint in degenerative eye diseases.

The entire intestinal epithelium is renewed every week due to cell division in the crypts coupled with cell migration towards the villi and loss of cells by apoptosis at the tip of villi (Fig. 1A).

SAN FRANCISCO, CA — Researchers at the Gladstone Institutes and University of California, San Francisco have shown that a loss of cells in the retina is one of the earliest signs of frontotemporal dementia (FTD) in people with a genetic risk for the disorder — even before any changes appear in their behavior.

There are many unpleasant human diseases that reflect the loss of cells that are not replaced, these include Parkinson's, diabetes, spinal chord injury, and some forms of blindness.

Enumeration of 33D1 + DCs showed a significant reduction of positive cells in the spleen, confirming that the reduction in CD4 + DCs is due to a loss of this cell type rather than being due to a reduction in surface marker expression (Figure 1F).

In the majority of pets that develop Addison's disease, the problem is destruction or loss of the cells that produce cortisol and aldosterone in the adrenal cortex.

If this loss of cells happens quickly, the dog is in acute renal failure.

Once exposed to the virus, the loss of cells causes complications and bacterial infections.