Sentences with phrase «low affinity»

Patients with low affinity, on the other hand, displayed a considerably higher level of insulin production, which remained constant over a time frame of 30 months.

Speaking of which, the Freeze Daggers are well balanced but the Diablos Hatchets have higher attack power and a defense bonus at the cost of lower affinity and requiring the Free Element skill to activate its ice element.

A research group led by Ryo Shinnakasu, Assistant Professor and Tomohiro Kurosaki, Professor at IFReC and a group at RIKEN Center for Integrative Medical Sciences jointly clarified that germinal - center B cells with lower affinity maturation of antigens were easily differentiation - induced into memory B cells.

Zheng is now trying to translate this finding to human pathology, where mutations in human ubiquitin ligases cause low affinity bindings to target proteins.

Low affinity germinal center B cells, which receive weaker stimulation from antigen and antigen specific CD4 T cells, maintain a relatively high level of Bach2 expression and tend to be induced to form memory B cells in the germinal center.

Although the kainate compounds do not have this problem, they have low affinity action only on one of the transporter subtypes.

This group clarified that germinal - center B cells with lower affinity maturation of antigens were easily differentiation - induced into memory B cells.

The Freeze Daggers are well balanced but the Diablos Hatchets have higher attack power and a defense bonus at the cost of lower affinity and requiring the Free Element skill to activate its ice element.

After adding a substance that causes digestive problems, the researchers said that the mice with a higher ability to bind ICZ to the AHR were protected from a chemical that induced digestive problems, but the mice with the lower affinity suffered from the toxic insult.

The group also found that the expression level of transcription factor Bach2 in germinal - center B cells with lower affinity was significantly high, and that this high expression of Bach2 was important for memory B cell differentiation.

The resulting antibody has a high affinity for the polymerized form of fibrin and a low affinity for the precursor material.

While most B cells have a low affinity for pathogens, which might effectively fend off a relatively mild virus, Tfh (with the stimulation of ICOS) allows the select few that produce highly specific and more strongly reactive antibodies to proliferate and outcompete their less specific brethren.

The closed form has a low affinity for MinD, i.e. the probability that it binds to MinD is quite small.

Interestingly, the GAD antibody affinity differed considerably even before the treatment, so that it was possible to distinguish between patients with high and low affinity.

This group also found that the expression level of transcription factor Bach2 in germinal - center B cells with lower affinity was significantly high and that this high expression of Bach2 was important for memory B cell differentiation.

We found here that light - zone (LZ) GC B cells with B cell antigen receptors (BCRs) of lower affinity were prone to enter the memory B cell pool.

The immune system of aged individuals often produces antibodies that have lower affinity and are less protective than antibodies from young individuals.

The most likely explanation for the poor effectiveness of vitamin D2 is that it binds with a lower affinity to the vitamin D - binding protein (DBP).

Albumin has the lowest affinity and the fastest release at tissue sites.

According to studies of healthy individuals in the United States, the Tg antibodies differ from those seen in Hashimoto's thyroididis patients, by being polyreactive, of lower affinity and of predominantly IgM isotype.

Also, the other inherent benefits of e-paper include a low affinity for battery drain while also being always on.

Theanine also increases brain dopamine levels and has a low affinity for AMPA, kainate, and NMDA receptors.»

That is because — in rabbits at least - there is some crossover effect («a lower affinity») on all the muscles of the body — not just the heart.

The low activity of these enzymes in the synthetic pathway, coupled with the low affinity of N acyltransferase for glycine for bile acid synthesis, results in the depletion of body taurine stores.

In contrast to cloud condensation nuclei, the most effective ice nuclei are hydrophobic (having a low affinity for water) with molecular spacings and a crystallographic structure close to that of ice.