Sentences with phrase «low cell toxicity»

According to the authors of the study, in future researches it will be necessary to know about the action mechanism of the new products - highly selective and with low cell toxicity on in vitro tests - and broaden preclinical studies with laboratory animal models.

The reagent is fully chemically defined and animal component - free, leading to increased reliability and low cell toxicity.

Not exact matches

Based on what is already known about fostamatinib toxicity, Shih says that patients using a combination of fostamatinib and paclitaxel may experience side effects that include low white blood cell counts, nausea, vomiting and diarrhea.

«The bacterial enzyme killed about 90 % of the MOLT4 human leukemia cells and displayed low toxicity to the healthy HUVEC cells, killing only 10 %,» Monteiro said.

EZ120 works in very small doses, is outstanding at entering tuberculosis pathogens, and has low toxicity toward human cells.

EZ120 is effective even in low doses, easily passes the mycomembrane and exhibits only low toxicity to human cells.

Such hybrid carriers have several advantages: low toxicity, efficient intracellular delivery and protection of siRNA against premature degradation prior to reaching the target cells.

Researchers at the University of Chicago Medical Center have isolated the gene for a component of the elusive molecular machinery that plays a key role in making cancer cells immortal, offering scientists a tantalizing target for new anticancer drugs of greater effectiveness and lower toxicity.

Some magnetic resonance techniques can give information about the quantity and function of beta cells, he says, but they use a dose of manganese chloride that is at least 1 million times higher than the new PET technique, suggesting an advantage in lower toxicity.

Combined with spinning confocal, it enables Super Resolution to be achieved at high speed and low photo - toxicity, making it the ideal solution for live high resoluion cell imaging.

In contrast, increasing progranulin levels via gene therapy effectively lowered amyloid beta levels, protecting against cell toxicity and reversing the cognitive deficits typically seen in these Alzheimer's models.

Thus, these approaches are characterized by inherent low toxicity and the possibility to use them in conjunction with conventional anti-cancer therapies targeting cancer cells such as radiation or chemotherapies.

[3] Low muscle mass is associated with increased risk of dose - limiting chemotherapy toxicities, such as low white blood cell count and reduced overall survival, and therefore it is extremely important to maintain muscle mass in advanced canceLow muscle mass is associated with increased risk of dose - limiting chemotherapy toxicities, such as low white blood cell count and reduced overall survival, and therefore it is extremely important to maintain muscle mass in advanced cancelow white blood cell count and reduced overall survival, and therefore it is extremely important to maintain muscle mass in advanced cancers.

In fact, in one study, a dose of mercury sufficient to kill 1 percent of lab rats (lethal dose «LD01»), when combined with a dose of lead sufficient to kill 1 percent, killed 100 percent of the rats.13 A similar test involving mercury and aluminum in cultured neurons killed 60 percent of the cells when the two low - dose toxicants (LD01) were combined.14 Even antibiotics have been shown to enhance the uptake, retention and toxicity of mercury.14 Additionally, testosterone appears to aggravate mercury toxicity during development, while estrogen protects against it.15 This may explain why more boys than girls are diagnosed with autism spectrum disorders and attention deficit disorders.